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Our Mission

To serve patients, health care providers, research scientists, scholars, and society by providing excellence and innovation in diagnostic services and educational resources in a respectful, professional and culturally diverse atmosphere.

Our Vision

To become a preeminent leader in academic anatomic and clinical pathology while translating basic science discovery to improved clinical care.

Frederick S. Nolte, Ph.D., D - Professor and Director of Clinical Laboratories

Frederick S. Nolte, Ph.D., D(ABMM), F(AAM)

Director of Clinical Laboratories
Director of Molecular Pathology
Department of Pathology & Laboratory Medicine
Office: Childrens Hospital Room 305
Phone: (843) 792-5020
Fax: (843) 792-7060


Medical Microbiology
Molecular Pathology
Laboratory Management


B.S., 1974, University of Cincinnati (OH)
Ph.D., 1980, Ohio State University
PostDoctoral Fellow 1980-1982, University of Rochester (NY)
Diplomate, 1985, American Board of Medical Microbiology
Fellow, 2002, American Academy of Microbiology


Infectious Disease, Diagnostics
Molecular Diagnostics


  1. Nolte, F.S., D.J. Marshall, C. Raspberry, S. Schievelbein, G. Banks, G. A. Storch, M.Q. Arens, R. S. Buller, and J. Prudent. 2007. Multicode PLx system for detection of respiratory viruses. J. Clin. Microbiol. 45:2779-2786.
  2. Sheppard C., Franks N., F.S. Nolte, and C.R. Fantz. 2008. Improving quality of patient care in an emergency department: a laboratory perspective. (2008) Am. J. Clin. Pathol. 130(4):573-577.
  3. Ahsanuddin, A.N., M.C. Standish, A.M. CaliEndo, C.E. Hill and F.S. Nolte. 2008. Validation of an Epstein-Barr viral load assay using the QIAGEN Artus EBV TM PCR analyte-specific reagent. Am. J. Clin. Pathol. 130:865-869.
  4. Nolte, F.S. 2008. Molecular diagnostics for detection of bacterial and viral pathogens in community-acquired pneumonia. Clin. Infect. Dis. 47 (Suppl 3): S123-S126.
  5. Spencer, D.V., F.S. Nolte, Y. Zhu. 2009. Heterophilic antibody interference causing false-positive rapid human immunodeficiency virus antibody testing. Clinica Chimica Acta 399:121-122.
  6. Cole, J.M., A.N. Schuetz, C.E. Hill, F.S. Nolte. 2009. Development and evaluation of a real-time PCR assay for detection of Klebsiella pneumoniae carbapenemase genes. J. Clin. Microbiol. 47:322-326.
  7. Sujatha M., A. A. Langston, F.S. Nolte, G. Banks, R. Martin, A.M. CaliEndo. 2009. Detection of respiratory viruses with a multiplex polymerase chain reaction assay (Multicode-PLx respiratory virus panel) in patients with hematologic malignancies. Leukemia & Lymphoma. 50:619-624.
  8. Schuetz A.N., R.L. Hughes, R.M. Howard, T.C. Williams, F.S. Nolte, D. Jackson, and B.S. Ribner. 2009. Pseudo-outbreak of Legionella pneumophila serogroup 8 infections associated with a contaminated ice machine in a bronchoscopy suite. Infect. Control. Hosp. Epidemiol. 30:461-466.
  9. Moreira, R.K., C. Norten, F.N. Rosado, C. Cohen, and F.S. Nolte. 2010. Histopathologically documented gastrointestinal cytomegalovirus infection in immunosuppressed patients: Clinicopathologic analysis with serum quantitative PCR correlation. Int. J. Med. Med. Sci. 2:49-59.
  10. Nolte, F.S., B.B. Rogers, Y.-W. Tang, M.S. Oberste, C.C. Robinson, K.S. Kehl, K.A. Rand, H.A. Rotbart, J.R. Romero, A.C. Nyquist, and D.H. Persing. 2011. Evaluation of a rapid and completely automated real-time reverse transcriptase PCR assay for diagnosis of enteroviral meningitis. J. Clin. Microbiol. 49:528-533.

Pathology Divisions
Anatomic Pathology
Laboratory Medicine

Department of Pathology and Laboratory Medicine Chairman Dr. Steven L. Carroll
Message from the Chairman


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