From Kirkcaldie MTK, Pridmore SA, Pascual-Leone A. Transcranial magnetic stimulation as therapy for depression and other disorders. Australian and New Zealand Journal of Psychiatry 1997;31:264-272:
| Study | Rate | Strength | Number | n | Measure | Outcome |
|---|---|---|---|---|---|---|
| Höflich et al. 1993 | 0.3 Hz (+ ECT) | 0.75-1.5 T; 105-130% Tm | 25 x 10 sets x 5 days x 2 wks | 2 | HDRS | 2 slight improvement; possible ECT priming |
| Grisaru et al. 1994 | 0.017 Hz? | 2 T | 60 in 60 min | 10 | HDRS; BPRS | 5 no change; 1 worse; 4 slight improvement |
| Kolbinger et al. 1995 | 0.25 - 0.5 Hz | control / above Tm / below Tm | 250 x 5 days | 15 | HDRS; self-rating | Slight (non-sig) improv in both treatment groups |
| George et al. 1995 | 20 Hz | 80% Tm | 40 x 20 sets x 5+ days | 6 | Clinical; HDRS | 2 no change; 2 slight improv; 2 robust improv |
| George et al. 1996 | 20 Hz | 80% Tm | 40 x 20 sets x 2 weeks | 12 | Clinical; HDRS | Sig group improvement; 25% HDRS red'n for 4 |
| Pascual-Leone et al. 1996 | 10 Hz | Tm | 100 x 20 sets x 5 days x 5 sites | 17 | HDRS; BDI | Sig reduction on both after LDPFC stimulation |
Abbreviations: ECT: electroconvulsive therapy; Tm: threshold of motor response; T: Tesla; HDRS: Hamilton Depression Rating Scale; BPRS: Brief Psychiatric Rating Scale; BDI: Beck Depression Inventory; LDPFC: left dorsolateral prefrontal cortex.