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Protein purifications

For new proteins, there is an initial $300 fee to perform a test expression and preliminary purification. If the system appears suitable for protein production, a quote will be prepared, which is based on the expected number of purification steps required. This quote must be approved by the investigator prior to any work commencing.

 

1-6 litres

One column prep - $300

Every additional column - $100

Refolding from inclusion bodies - $100

These fees include media preparation, cell growth & induction, harvesting, lysis, gel electrophoresis, and buffer exchange/concentration of the final protein (if desired)

7-12 litres

One column prep - $350

Every additional column - $100

Refolding from inclusion bodies - $100

(prep also includes media preparation etc., as above)

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Column only

To run a single column only, including SDS-PAGE - $100

 

Circular dichroism

$25 per hour instrument time

 

Crystallization

Crystal Screens I and II, JCSG screen (192 conditions) - $200

Each additional screen of 48 conditions - $50

(includes screens, plasticware and labor)

The crystal trays will be stored in the X-ray crystallography facility and can be monitored by the investigator or Dzmitry.

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