Recent Selected Publications

Nephrology
Proteomics

MUSC Nephrology Proteomics Facility

To contact us:
Director: John Arthur
             e-mail: arthurj@musc.edu
Associate Director: Michael Janech
             e-mail: janechmg@musc.edu
Lab Manager: Alison Bland
             e-mail: blanda@musc.edu

Arthur, J.M., V. Thongboonkerd, J.A. Scherzer, J. Cai, W.M. Pierce and J.B. Klein. Differential expression of proteins in renal cortex and medulla: A proteomic approach. Kidney Int. 62:1314-21, 2002. Abstract

Thongboonkerd, V.,K.R. McLeish, J.M. Arthur, and J.B. Klein Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney Int. 62:1461-9, 2002. Abstract

Thongboonkerd, V., E Gozal, L. Sachleben, Jr., J.M. Arthur, W.M. Pierce, J. Cai J. Chao, D. Gozal, and J.B. Klein Proteomic analysis reveals differential regulation of renal kallikrein system during episodic and sustained hypoxia.. J. Biol. Chem. 277:34708-34716, 2002. Abstract

Arthur, J.M. Proteomics. Current Opinions in Nephrology and Hypertension. 12:423-430, 2003. Abstract

Thongboonkerd, V, J.B. Klein., Pierce, W.M, Jevans,A.W. and J.M. Arthur Sodium Loading Changes Urinary Protein Excretion: A Proteomic Analysis, Am. J. Physiol, 284: F1155-F1163, 2003 Abstract

Thongboonkerd, V., J.B. Klein and J.M. Arthur. Proteomic Identification of a large complement of rat urinary proteins. Nephron Exp. Nephrol. 95:e69-e78, 2003. Abstract

Stanislaus, R. Jiang. L.H., Swartz,M., Arthur, J.M. and J. Almeida. An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry. BMC Bioinformatics 5:9, 2004 Abstract

D.M. Lefler,D.G. Pafford, N. Black, J.R. Raymond and J.M. Arthur. Identification of proteins in slow continuous ultrafiltrate by reverse phase chromatography and proteomics. J. Proteome Res. 3:1254, 2004. Abstract

J.S Almeida, R. Stanlislaus, E. Krug, J.M. Arthur. Normalization and analysis of residual variation in 2D Gel Electrophoresis for quantitative differential proteomics. Proteomics, 5:1242-1249, 2005. Abstract

Stanislaus R, C Chen, J Franklin, J M. Arthur, JS Almeida. AGML central: web based gel proteomic infrastructure. Bioinformatics, 21:1754-1757, 2005. Abstract

Oates, J.C., S. Varghese, A.M. Bland, T.P. Taylor, S.E. Self, R. Stanislaus, J.S. Almeida and J.M. Arthur. Prediction of urinary protein markers in lupus nephritis. Kidney Int. 68:2588-2592, 2005. Abstract

Bland, A.M., L.R. D'Eugenio, M.A. Dugan, M.G. Janech, J.S. Almeida, M. Zile, and J.M. Arthur. Comparison of Variability Associated with Sample Preparation in Two-Dimensional Gel Electrophoresis of Cardiac Tissue. J. Biomol. Tech. 17:195-199, 2006. Abstract

Almeida, J.S., J.C. Oates, and J.M. Arthur. How to Evaluate the Quality of Predictive Models for Classification. Kidney Int. 70:232, 2006. Abstract

Janech, M.G., Raymond, J.R., and J.M. Arthur. Proteomics in renal research. Am. J. Physiol. Renal Physiol. 292:F501-F512, 2007. Abstract

Varghese, S.A., T.B. Powell, M.N. Budisavljevic, J.C. Oates, J.R. Raymond, J.S. Almeida and J.M. Arthur. Urine biomarkers predict the cause of glomerular diseases. J. Am. Soc. Neph. 18:913-922, 2007. Abstract

Velez, JCQ, AM Bland, JM Arthur, JR Raymond and MG. Janech. Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. Am. J. Physiol. Renal Physiol. 293:F398-407, 2007. Abstract

Stanislaus, R., J.M. Arthur , B. Rajagopalan , R. Moerschell , B. McGlothlen and J.S. Almeida. An open-source representation for 2-DE-centric proteomics and support infrastructure for data storage and analysis. BMC Bioinformatics, 9:4, 2008.  Abstract

Arthur, J.M., M.G. Janech, S.A. Varghese and T.B Powell. Diagnostic and prognostic biomarkers in acute renal failure. Contrib. Nephrol. 160:53-64, 2008.  Abstract

Selected Book Chapters

Raymond, J.R., Turner, J., Ayiku, H., Lefler, D., Gelasco, A., Arthur, J.M. Use of mass spectrometry to identify receptor-interacting proteins. In: G Protein-coupled Receptor Interacting Proteins. (George, S., O'Dowd, B, and Sibley, D., Eds.). Wiley Press, Indianapolis. 2005.

Raymond, J.R., Turner, J., Gelasco, A, Ayiku, H., Coaxum, S., Arthur, J.M. and Garnovskaya, M.N. 5-HT Receptor Signal Transduction Pathways. In:The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics. Ed B.L. Roth, pp. 143-206. The Humana Press, Inc., Totowa, NJ, 2006.

Arthur, J.M. and Powell T.B. Urinary Biomarkers in Diabetes and Other Glomerular Diseases. In: Clinical Proteomics: From Diagnosis to Therapy. Ed J. Van Eyk and M. Dunn, pp. 297-322. Wiley-VCH, Weinheim, 2008.

Arthur, J.M., M.N. Budisavljevic, S.A. Varghese and T.B. Powell. Proteomics and Acute Renal Failure. In: Critical Care Nephrology. Ed C. Ronco, R. Bellomo, and J. Kellum. In Press 2008.