Membrane Proteins

As stated above, integral membrane proteins present greater challenges not only for the mass spectrometry, but also for the preceding peptide chemistry. The MUSC laboratory has a particular interest in membrane receptor proteins. Work is underway to develop improved procedures for protein cleavage and sample preparation for mass spectrometry of integral membrane proteins and their peptide cleavage products. Recent developments in HPLC separations of cyanogen bromide cleavage products promise to greatly expedite our work on membrane proteins.

We are located in room 305 of the Children's Research Institute Building at MUSC.

Biomolecular Mass Spectrometry Facility Department of Pharmacology Medical University of South Carolina 173 Ashley Avenue, CRI 305 Charleston, SC 29425	Telephone Numbers: 843-792-5849 (CRI 305) 843-792-2471 (department office) FAX: 843-792-2475