Frederick S. Nolte, Ph.D., D(ABMM), F(AAM)

Professor
Director of Clinical Laboratories
Department of Pathology & Laboratory Medicine
Office: Childrens Hospital Room 305
Phone: (843) 792-5020
Fax: (843) 792-7060

CLINICAL EXPERTISE:

Medical Microbiology
Molecular Pathology
Laboratory Management

EDUCATION:

B.S., 1974, University of Cincinnati (OH)
Ph.D., 1980, Ohio State University
Postdoctoral Fellow 1980-1982, University of Rochester (NY)
Diplomate, 1985, American Board of Medical Microbiology
Fellow, 2002, American Academy of Microbiology

RESEARCH INTERESTS:

Infectious Disease, Diagnostics
Molecular Diagnostics

RECENT PUBLICATIONS:

1. Hill, C.E., S.B. Harris, E.E. Culler, J.C. Zimring, F.S. Nolte, and A.M. Caliendo. 2006. Performance characteristics of two real-time PCR assays for the quantification of Epstein-Barr virus DNA. Am. J. Clin. Pathol. 125:665-671.
2. Hill, C.E., A. Duncan, D. Wirth, and F.S. Nolte. 2006. Detection and identification of cytochrome P450 2C9 alleles *1, *2, and *3 by high resolution melting curve analysis of PCR amplicons. Am. J. Clin. Pathol. 125:584-591.
3. Nolte, F.S. 2006. Case studies in cost effectiveness of molecular diagnostics for infectious diseases: Pulmonary tuberculosis, enteroviral meningitis, and BK virus nephropathy. Clin. Infect. Dis. 43: 1463-1467.
4. Kost, C.B., B. Rogers, M.S. Oberste, C. Robinson, B.L. Eaves, K. Leos, S. Danielson, M. Satya, F. Weir, and F.S. Nolte. 2007. A multi-center beta trial of the GeneXpert enterovirus assay. J. Clin. Microbiol. 45:1081-1086.
5. Ferguson, T.D., S. Schniederjen, J. Dionne-Odom, M.E. Brandt, M.G. Rinaldi, F.S. Nolte, A. Langston, and S. Zimmer. 2007. Posaconazole for Apophysomyces elegans rhino-orbital zygomycosis in a well-controlled diabetic male. J. Clin. Microbiol. 45:1648-1651.
6. Nolte, F.S., D.J. Marshall, C. Raspberry, S. Schievelbein, G. Banks, G. A. Storch, M.Q. Arens, R. S. Buller, and J. Prudent. 2007. Multicode PLx system for detection of respiratory viruses. J. Clin. Microbiol. 45:2779-2786.
7. Marshall, D.J., E. Reisdorf, G. Harms, E. Beaty, M.J. Moser, W.M. Lee, J.E. Gern, F.S. Nolte, P. Shult, and J. Prudent. 2007. Evaluation of a multiplexed PCR assay for detection of respiratory viral pathogens in a public health laboratory setting. J. Clin. Microbiol. 45:3875-3882.
8. Hidron, A., A. Schuetz, F.S. Nolte, C. Gould, and M.K. Osborn. 2008. Daptomycin resistance in Enterococcus faecalis prosthetic valve endocarditis. J. Antimicrob. Chermother. doi: 10.1093/jac/dkn105.
9. Nolte, F.S. 2008. Molecular diagnostics for bacterial and viral pathogens in community-acquired pneumonia. (2008) Clin. Infect. Dis. (in press).
10. Sheppard, C.A., N. M. Franks, F.S. Nolte, and C.R. Fantz. 2008. Improving quality of patient care in an emergency department: A laboratory perspective. (2008) Am. J. Clin. Pathol. (in press)