Yusheng Zhu, Ph.D., DABCC, FACB

Associate Professor
Director of Clinical Chemistry & Toxicology
Department of Pathology & Laboratory Medicine
Office: Childrens Hospital Room 326B
Phone: (843) 792-8814
Fax: (843) 792-0424

EDUCATION:

Ph.D., 1999, Shanghai Medical University, Shanghai, China
MS, 1995, Shanghai Medical University, Shanghai, China
Post-Doctoral Research Associate, 2000-2003, University of Georgia. Athens, GA
Clinical Chemistry and Toxicology Fellowship, 2003-2005, University of Louisville School of Medicine, Louisville, KY
Pharmacogenetics Fellowship, 2005-2006, University of Louisville School of Medicine, Louisville, KY

RESEARCH INTERESTS:

Pharmacogenomics
Development of SNP typing assays
Clinical application of SELDI-TOF mass spectrometry
Clinical proteomics

RECENT PUBLICATIONS:

1. Su Z, Slay BR, Carr R, Zhu Y. The recognition of 25-hydroxyvitamin D2 and D3 by a new binding protein based 25-hydroxyvitamin D assay. Clin Chim Acta 2013,417:62-66 .
2. Su Z, Graybill WS, Zhu Y. Detection and monitoring of ovarian cancer. Clin Chim Acta 2013, 415: 341-5.
3. Sofronescu AG, Loebs T, Zhu Y. Effects of temperature and light on the stability of bilirubin in plasma samples. Clin Chim Acta 2012, 413:463-466.
4. Alina-Gabriela Sofronescu, Laurie M. Williams, Dorinda M. Andrews, Yusheng Zhu. Unexpected hemoglobin A1c results. Clinical Chemistry 2011;57:153-156.
5. Laura Spruill, Mary A. Constantin, Dorinda M. Andrews, Zhu, Yusheng. Heterophilic antibody interference in a chemiluminescent immunometric erythropoietin assay. Clin Chim Acta 2010,411:1156-7.
6. Yusheng Zhu, Laurie M. Williams, Beverly D. Horne. Disparity in estimated average glucose due to different hemoglobin A1c assays and hemoglobin S trait. Clin Chem Lab Med. 2010;48(4):571-2
7. Yusheng Zhu, Laurie M. Williams. Falsely elevated hemoglobin A1c due to S-b+-thalassemia interference in Bio-Rad VARIANT II TURBO HbA1c assay. Clin Chim Acta 2009, 409:18-20.
8. Deborah V. Spencer, Frederick S. Nolte, Zhu, Yusheng. Heterophilic Antibody Interference Causing False-Positive Rapid Human Immunodeficiency Virus Antibody Testing. Clin Chim Acta 2009, 399(1-2):121-2.
9. Zhu, Yusheng, Marilyn M. Jenkins, Darby A. Brass, Precila G. Ravago, Beverly D. Horne, Sharron B. Dean, Nancy Drayton. Heterophilic antibody interference in an ultra sensitive three-site sandwich troponin I immunoassay. Clin Chim Acta 2008, 395(1-2):181-2
10. Zhu, Yusheng, Michael Shennan, Kristen K. Reynolds, Nancy A. Johnson, Matthew R. Herrnberger, Roland Valdes Jr., Mark W. Linder. Estimation of warfarin maintenance dose based on VKORC1 (-1639G>A) and CYP 2C9 genotypes. Clinical Chemistry 2007, 53(7):1199-1205
11. Zhu, Yusheng, David W. Hein, Mark A. Doll, Abudu, N., Valdes, R. Jr., Linder, M. Simultaneous determination of N-acetyltransferase-2 (NAT2) polymorphisms by allele-specific primer extension assay. Clinical Chemistry 2006, 52(6):1033-9
12. Zhu, Yusheng, Valdes, R. Jr., Simmons, C. Q, Jortani, S. A. Analysis of ligand binding by bioaffinity mass spectrometry, Clin Chim Acta 2006, 371(1-2):71-8
13. Zhu, Yusheng, Elin, R.J. Ethanol treatment of serum produces a spurious band on electrophoresis. Clin Chim Acta 2006;366(1-2):341-3.
14. Zhu, Yusheng, Valdes, R. Jr., Jortani, S. A. Application of bioaffinity SELDI-TOF mass spectrometry, Therapeutic Drug Monitoring 2005;27(6):694-9.
15. Zhu, Yusheng, Tomlinson, R. L., Terns, R. M., Terns, M. P. Telomerase RNA accumulates in Cajal bodies in human cancer cells. Molecular Biology of the Cell 2004, 15: 81-90
16. Etheridge, K.T., Banik, S. S. R., Armbruster, B. N., Zhu, Yusheng, Terns, R. M., Terns, M. P., Counter, C. M. The nucleolar localization Domain of the catalytic subunit of human telomerase. The Journal of Biological Chemistry 2002, 277 (27): 24764-70