To serve patients, health care providers, research scientists, scholars, and society by providing excellence and innovation in diagnostic services and educational resources in a respectful, professional and culturally diverse atmosphere.
Our Vision
To become a preeminent leader in academic anatomic and clinical pathology while translating basic science discovery to improved clinical care.
Mako Ogawa, M.D., Ph.D.
Hans and Helen Koebig Professor, Department of Pathology & Laboratory Medicine
Office: Ralph H. Johnson VA Medical Center Research Services Room 151
Phone: (843) 789-6712
Fax: (843) 876-5381
EDUCATION:
1958-1964 M.D., Osaka University Medical School, Osaka, Japan
1970-1973 Ph.D., University of Toronto, Institute of Medical Science, Toronto, Canada
CLINICAL TRAINING:
1964-1965 - Rotating Intern, US Naval Hospital, Jokosuka, Japan
1965-1966 - Resident in Medicine, The Third Department of Internal Medicine, Osaka University Hospital, Osaka, Japan
1966-1968 - Resident in Medicine, Dartmouth Medical School Affiliated Hospitals, Hanover, NH
1968-1970 - Fellow in Hematology, Department of Medicine, Dartmouth Medical School, Hanover, NH
RESEARCH INTERESTS:
My research interest has been in the cellular physiology of hematopoietic stem cells (HSCs). Current focus is in the tissue reconstituting potentials of HSCs.
SELECTED PUBLICATIONS:
LaRue AC, Masuya M, Ebihara Y, Fleming PA, Visconti RP, Ogawa M, and Drake, CJ: Hematopoietic origins of fibroblasts: I. In vivo studies of fibroblasts associated with solid tumors. Exp Hematol 34:208-218, 2006.
Ebihara Y, Masuya M, LaRue AC, Yang S, Owens RW, Argraves K, Visconti RP, Fleming PA, Minamiguchi H, Hill WD, Martin-Studdard A, Drake CJ, Ogawa M: Hematopoietic origin of fibroblasts: II. In vitro studies of fibroblasts, CFU-F and fibrocytes. Exp Hematol 34:219-229, 2006.
Lang H, Ebihara Y, Schmiedt R, Minamiguchi H, Zhou D, Smythe N, Liu L, Ogawa M, Schulte B: Contribution of bone marrow hematopoietic stem cells to adult mouse inner ear: Mesenchymal cells and fibrocytes. J Comp Neurol 496:187-201, 2006.
Visconti RP, Ebihara Y, LaRue AC, Fleming PA, McQuinn TC, Masuya M, Minamiguchi H, Markwald RR, Ogawa M, Drake CJ: An in vivo analysis of hematopoietic stem cell potential: Hematopoietic origin of cardiac valve interstitial cells. Circ Res 98:690-696, 2006
Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood 107:358-366, 2006.
Ogawa M, LaRue AC, Drake CJ: Hematopoietic Origin of Fibroblasts/Myofibroblasts: Its Patho-physiological Implications. Blood 108:2893-2896, 2006.
LaRue AC, Ogawa M: Hematopoietic origin of fibrocytes. IN: Fibrocyets: New Insights into Tissue Repair and Systemic Sclerosis, Bucala R (ed), World Scientific Publishing Co., Singapore, 2007, pp 61-74.
Ogawa M, LaRue AC: Origin of fibroblast colony-forming units. Exp Hematol 35: 1319-1320, 2007
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