THE DEPARTMENT OF
PATHOLOGY AND LABORATORY MEDICINE

The Department is composed of four divisions: Anatomic Pathology, Clinical Pathology, Research, and Education. The Department employs 47 full-time faculty, and is responsible for the operation of diagnostic laboratories in Surgical Pathology, Autopsy Pathology, Forensic Pathology, Molecular Pathology, Cytology, Cytogenetics, Immunopathology, Hematology, Transplantation and Transfusion Medicine, Diagnostic Immunology, Clinical Chemistry and Clinical Microbiology. The combination of the clinical and basic sciences in the Department keeps students in close touch with current medical problems as they initiate and perform their research.

The research equipment available within the Department of Pathology and Laboratory Medicine reflects the diversity of the Department. Major equipment and facilities include: molecular biology facilities, protein purification and analysis equipment, transmission electron microscopy including x-ray microanalysis, freeze fracture and cryoultramicrometry facilities, tissue culture and tumor bank facilities, histopathology facilities, image processing and analysis facilities, laser capture microdissection, microscopy fluorometry, single cell microinjection, and time-lapse video imaging.

Faculty within the Department of Pathology and Laboratory Medicine are listed below:

DIVISION OF ANATOMIC PATHOLOGY

Janice M. Lage, M.D., Chair

Masha H. Bilic, MD - Instructor

Michael J. Caplan - Assistant Professor

Christina Carrick, MD - Assistant Professor

Kim A. Collins, M.D. - Professor

Haytham Dimashkieh, MD - Instructor

Russell A. Harley, M.D. - Human and Experimental Pulmonary Pathology

David N. Lewin, M.D. - Residency Program Director
Gastrointestinal, Pancreatic, and Hepatopathology

Jim Madory, D.O. - Director, Pathology Informatics

John S. Metcalf, M.D. Department Vice-Chair
Dermatopathology, pathophysiology of melanoma

S. Erin Presnell, M.D. - Director, Medical and Forensic Autopsy; Director, Undergraduate Education

Mary S. Richardson, M.D. - Director, Surgical Pathology

Cynthia A. Schandl, Ph.D., M.D. - Director, Forensic Pathology Fellowship Program
General Forensic Pathology, Maternal and Placental Pathology, Forensic Histopathology, Molecular Forensic Pathology, Molecular Surgical Pathology

M. Timothy Smith, M.D. - Director, Anatomical Pathology
Surgical Pathology, Neuropathology, Dermatopathology

Cynthia Welsh, M.D. - Neuropathology

Jack Yang, M.D. - Associate Professor and Acting Director, Cytology

DIVISION OF CLINICAL PATHOLOGY

Janice M. Lage, M.D., Chair

John Lazarchick, M.D. - Vice Chair, Clinical Pathology; Director, Hematology & Hematopathology Fellowship Program

Frederick S. Nolte, Ph.D. - Professor and Director of Clinical Laboratories

Christine N. Papadea, Ph.D. - Special Chemistry, Toxicology

Denise I. Quigley, Ph.D. - Associate Director of Cytogenetics and Molecular Pathology Laboratories

Sally E. Self, M.D. - Director, Flow Cytometry, Immunology

Jerry E. Squires, M.D., Ph.D. - Medical Director, Transfusion Service

Lisa L. Steed, Ph.D.- Director, Microbiology

Daynna Wolff, Ph.D. - Director, Molecular Pathology

Yusheng Zhu, Ph.D. - Director of Clnical Chemistry and Toxicology

DIVISION OF RESEARCH PATHOLOGY

Janice M. Lage, M.D., Chair

Bradley A. Schulte, Ph.D. Vice Chair , Division of Research
Molecular mechanisms of fluid and ion transport in health and disease, histochemical techniques in cell and molecular biology.

Erika T. Brown, Ph.D. - Cancer biology, DNA damage and repair

Lisa Cunningham, Ph.D. - Ototoxicity, Apoptosis in inner ear hair cells

Vincent Dammai, M.Phil, Ph.D. - Cell adhesion, intracellular protein trafficking and tumor metastasis

Weimin Fan, M.D. - Hormonal carcinogenesis, genetic control of cell cycle arrest, drug-induced apoptosis.

Debra J. Hazen-Martin, Ph.D. - Heavy-metal nephrotoxicity, epithelial cell culture and ultrastructure.

Kris Helke, DVM, Ph.D. - Neurogeneration, Animal Diseases

Tien Hsu Ph.D. - Epithelial morphogenesis and cell migration in development and in cancer

Toshihiko Kawamori, M.D., Ph.D. - Cancer chemoprevention, arachidonic acid cascade and cancer development

Hainan Lang, M.D., Ph.D.- Cellular and molecular mechanisms of sensorineural hearing loss; stem cell therapy in hearing loss

Amanda C. LaRue, Ph.D. - Tissue reconstituting potentials of hematopoietic stem cells (HSCs)

Runzhao Li, M.D.- Epithelial-to-Mesenchymal Transition and Tumor Metastasis

Omar Moussa, M. Sc., Ph.D. - Gene expression, Molecular Profiling, Ets Transcription

Makio Ogawa, M.D., Ph.D. - Tissue Reconstituting Potentials of HSCs

Gian G. Re, Ph.D. - Gene expression in cancer.

Dr. Demetri Spyropoulos

Meihua Sui, M.D. - Cancer biology and experimental therapeutics

Yong Wang, M.D., Ph.D. - Cancer therapy-induced normal tissue injury, hematopoietic stem cell biology; molecular radiobiology

Dennis Watson, Ph.D. - Molecular biology of gene regulation, molecular genetics of cancer.

Ling Wei, M.D. - Stroke and cell death, stem cell transplantation after brain injury, neurovascular plasticity and functional recovery.

Daohong Zhou, M.D. - Radiation therapy for cancer, cellular mechanisms

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