MECHANISMS OF DISEASE (PATH602)
Fall, 2008

Lecture/Demonstrations in Basic Sciences Auditorium;
Labs/Seminar-Tutorial on 1st Floor, Walton Research Building

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Date Day Time Lecture Lecturer
Aug 19 T 8-8:50 Introduction Presnell
9-9:50 Autopsy and Forensic Pathology Presnell
10-10:50 Cell Injury I Hazen Martin
Aug 20 W 8-8:50 Cell Injury II Hazen-Martin
Aug 21 Th 8-8:50 Lab Study  
9-9:50 Inflammation I Hazen-Martin
10-10:50 Inflammation  II Hazen-Martin
11-11:50 Introduction to Medical Genetics (Jorde Ch. 1,14) Pai

WEEK 2

Aug 25

M

8-8:50  

Inflammation III

Hazen-Martin

Aug 26

T

8-8:50

Repair

Hazen-Martin

9-9:50

Hemodynamic Disorders I

Hazen-Martin

11-11:50

Medical Genetics – Jorde Ch.  4
Groups 1-7: COW (Osteogenesis Imperfecta)
Groups 8-14: AD/AR Inheritance/Population Genetics/Epigenetics (Quigley)

Aug 27

W

8-8:50

Hemodynamic Disorders II

Hazen-Martin

Aug 28

Th

8-8:50

Embolism, Infarction, Shock

Hazen-Martin

11-11:50 Medical Genetics – Jorde Ch. 4
Groups 1-7: AD/AR Inheritance/Population Genetics/Epigenetics (Quigley)
Groups 8-14: COW (Osteogenesis Imperfecta)

Genetics

Answer to Review Questions * Fact Sheet for COW 1

WEEK 3

Sept 1

M

 

LABOR DAY – NO CLASSES

Sept 2

T

8-8:50

Arteriosclerosis & Hypertension

Hazen-Martin

9-10:50

Groups 1-7: ST Case #1: Indigestion; Shortness of Breath
Groups 8-14: Lab Study 1

11-11:50

Medical Genetics – Jorde Ch.  5
Groups 1-7: COW (Duchenne’s Muscular Dystrophy)
Groups 8-14: Sex-linked and Mitochondrial Inheritance (Quigley)

Sept 3

W

8-8:50

Lab Study 1

Sept 4

Th

9-10:50

Groups 1-7: Lab Study 1
Groups 8-14: ST Case #1: Indigestion; Shortness of Breath

11-11:50

Medical Genetics – Jorde Ch.  5
Groups 1-7: Sex-linked and Mitochondrial Inheritance (Quigley)
Groups 8-14: COW (Duchenne’s Muscular Dystrophy)

Genetics Answer to Review Questions * Fact Sheet for COW 2

WEEK 4

Sept 8

M

8-8:50

Environmental Pollution and Pneumoconiosis

Presnell

Sept 9

T

9-9:50

Environmental Pathology: Chemical Injury

Presnell

10-10:50

Environmental Pathology: Physical Injury

Presnell

11-11:50

Medical Genetics – Jorde Ch.  12
Groups 1-7: COW (Alzheimer Disease)
Groups 8-14: Multifactorial Disease (Pai)

Sept 10

W

8-8:50

Environmental Pathology Review

Presnell

8-10:50

Make-up Time for Dr. Virella's Canceled Friday 8/4/08 class (Hanna)

Sept 11

Th

8-8:50

Infectious Diseases

Schandl/Steed

10-10:50

Transplantation I (Baliga PPT)

Self

11-11:50

Medical Genetics – Jorde Ch. 12
Groups 1-7: Multifactorial Disease (Pai)
Groups 8-14: COW (Alzheimer Disease)

    Genetics Fact Sheet for COW 3

WEEK 5

Sept 15

M

8-8:50

Transplantation II

Self

9-9:50

Eye Pathology

Kini

Sept 16

T

8-8:50

Autoimmune Diseases I

Self

9-10:50

Groups 1-7: ST Case #2: Transplantation; Autoimmunity; Renal Failure; Shortness of Breath
Groups 8-14: Lab Study 2

11-11:50

Medical Genetics – Jorde Ch.  7
Groups 1-7: COW (Phenylketonuria)
Groups 8-14: Inborn Errors (PPT UPDATED)(Pai)

Sept 17

W

8-8:50

Autoimmune Diseases II

Self

Sept 18

Th

8-8:50

Amyloidosis and Immune Vasculitis

Self

9-10:50

Groups 1-7: Lab Study 2
Groups 8-14: ST Case #2: Transplantation; Autoimmunity; Renal Failure; Shortness of Breath

11-11:50

Medical Genetics – Jorde Ch.  7
Groups 1-7: Inborn Errors (PPT UPDATED) (Pai)
Groups 8-14: COW (Phenylketonuria)

Genetics Fact Sheet for COW 4 _ _ _ _ JAMA article

Sept 19

F

8-8:50

CPC 1

WEEK 6

PATH602:                                                           FIRST TERM TEST – September 26

WEEK 7

Sept 29

M

8-8:50

Pathology of Nutrition I                       

Schandl

9-9:50

Gram Stain Lab

Sept 30

T

8-8:50

Pathology of Nutrition II

Schandl

10-10:50

Lab Study 3

11-11:50

Medical Genetics – Jorde Ch. 2,3
Groups 1-7: COW (Prader-Willi/Angelman Syndrome)
Groups 8-14: Structure/Function Genes/Chroms (Wolff)

Oct 1

W

8-8:50

Gram Stain Lab

Oct 2

Th

8-8:50

Gram Stain Lab

9-9:50

Respiratory Infections I

Bilic

10-10:50

Respiratory Infections II

Bilic

11-11:50

Medical Genetics – Jorde Ch.  2,3
Groups 1-7: Structure/Function Genes/Chroms (Wolff)
Groups 8-14: COW (Prader-Willi/Angelman Syndrome)

Genetics Fact Sheet: Angelman Syndrome _ Fact Sheet: Prader-Willi Syndrome - Review Answers

WEEK 8

Oct 7

T

9-10:50

Groups 1-7: ST Case #3: Hemoptysis, Skin Lesions, Shortness of Breath & Fever, Shortness of Breath
Groups 8-14: Lab Study 3

11-11:50

Medical Genetics – Jorde Ch. 6
Groups 1-7: COW (Down Syndrome)
Groups 8-14: Chromosomes (Wolff)

Oct 8

W

8-8:50

GI Infections and Malabsorption

Lewin

9-9:50

Lab Study

Oct 9

Th

8-8:50

Neoplasia I

Lewin

9-10:50

Groups 1-7: Lab Study 3
Groups 8-14: ST Case #3: Hemoptysis, Skin Lesions, Shortness of Breath & Fever, Shortness of Breath

11-11:50

Medical Genetics – Jorde Ch. 6
Groups 1-7: Chromosomes (Wolff)
Groups 8-14: COW (Down Syndrome)

Genetics

Fact Sheet: Down Syndrome - Review Answers

WEEK 9

Oct 13

M

8-8:50

Neoplasia II

Lewin

Oct 14

T

8-8:50

Lab Study 4

9-9:50

Neoplasia III

Lewin

10-10:50

Neoplasia IV

Lewin

11-11:50

Medical Genetics – Jorde Ch. 11
Groups 1-7: COW (Breast Cancer of Neurofibromatosis)
Groups 8-14: Cancer Genetics (Hammond)

Oct 15

W

8-8:50

Respiratory Infections Recap - Dr. Bilic

Oct 16

Th

8-8:50

Lab Study 4

11-11:50

Medical Genetics – Jorde Ch. 11
Groups 1-7: Cancer Genetics (Hammond)
Groups 8-14: COW (Breast Cancer of Neurofibromatosis)

Genetics Fact Sheet: Inherited Breast & Ovarian Cancer

WEEK 10

Oct 20

M

8-8:50

Pediatric Diseases I

Batalis

Oct 21

T

8-8:50

Pediatric Diseases II

Batalis

9-10:50

Groups 1-7: ST Case #4: Vaginal Bleeding, Abdominal Mass, Liver Mass, Weakness & Anorexia, Features of Malignancy
Groups 8-14: Lab Study 4

11-11:50

Medical Genetics – Jorde Ch. 10
Groups 1-7: COW (Achondroplasia)
Groups 8-14: Developmental Genetics - updated (Wolff)

Oct 22

W

8-8:50

CPC 2

Oct 23

Th

8-8:50

Pediatric Diseases III

Batalis