
Selected
Publications:
Probin V, Wang Y and Zhou D. Busulfan-induced senescence
is dependent upon ROS production upstream of the MAPK pathway. Free
Radical Biology and Medicine, 42: 1858-1865, 2007.
Wang Y, Schulte BA, Larue AC, Ogawa M and Zhou D. Total
body irradiation selectively induces murine hematopoietic stem cell senescence. Blood,
107:358-66, 2006.
Probin V, Wang Y, Bai A, and Zhou D. Busulfan selectively
induces cellular senescence but not apoptosis in WI38 fibroblasts via
a p53-independent but Erk-p38 MAPK-dependent mechanism. J Pharmacol
Exp Ther, 319(2): 551-60, 2006.
Wang Y, Schulte BA, Zhou D. Hematopoietic stem cell
senescence and long-term bone marrow injury. Cell Cycle, 5:35-38,
2006.
Wang Y, Probin V and Zhou D. Cancer therapy-induced
residual bone marrow injury- Mechanisms of induction and implication
for therapy. Current Cancer Therapy Reviews, 2(3): 271-279,
2006.
Wang Y, Meng A, Lang H, Brown SA, Konopa JL, Kindy
MS, Schmiedt RA, Thompson JA, Zhou D. Activation of Nuclear Factor kB
in vivo Selectively Protects the Murine Small Intestine against Ionizing
Radiation-Induced Damage. Cancer Research, 64: 6240-6, 2004.
Wang Y, Meng A, Zhou D. Inhibition of phosphatidylinostol
3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest
in normal human diploid fibroblasts. Exp Cell Res, 298:188-96,
2004.
Bai A, Meier GP, Wang Y, Luberto C, Hannun YA, Zhou
D. Prodrug modification increases D609 chemical stability and cytotoxicity
against U937 leukemia cells. J Pharmacol Exp Ther, 309: 1051-9,
2004.
Meng A, Wang Y, Van Zant G, Zhou D. Ionizing Radiation
and Busulfan Induce Premature Senescence in Murine Bone Marrow Hematopoietic
Cells. Cancer Research, 63:5414-9, 2003.
Meng A, Wang Y, Brown SA, Van Zant G, Zhou D. Ionizing
Radiation and Busulfan Inhibit Murine Bone Marrow Cell Hematopoietic
Function via Apoptosis Dependent and Independent Mechanisms. Exp
Hematol, 31:1348-1356, 2003.
Meng A, Yu T, Chen G, Brown SA, Wang Y, Thompson JS,
Zhou D. Cellular Origin of IR-Induced NF-kB Activation in vivo and Role
of NF-kB in Ionizing Radiation-Induced Lymphocyte Apoptosis. Int
J Radiation Biol, 79:849-861, 2003.
Zhang B, Wang Y, Zheng GG, Ma XT, Li G, Wu KF. Clinical
significance of IL-18 gene over-expression in AML. Leukemia Res,
26: 887-92, 2002.
Wang Y, Li G, Zheng GG, Song YH, Wu KF. Detection and
sequencing analysis of IL-18 expression in J6-1 leukemic cells. Leukemia
Res, 25: 273-274, 2001.
Wang Y, Zheng GG, Wu KF, Li G and Rao Q. Construction
of macrophage colony-stimulating factor receptor DNA vaccine. Haematologica, 86:
1219-1220, 2001.
|