Gian G. Re, Ph.D.

Associate Professor of Pathology and Laboratory Medicine

Room 313 Walton Research Building


 

Phone: 843-792-3423

Fax: 843-792-0368


Education:

Research Interests: My laboratory is involved in two collaborative research projects. One collaborative project, with Dr. Bradley Schulte, deals with experimental and clinical studies of presbyacusis and is involved with the analysis of gene expression changes in human cochleas of different ages. The second project focuses on the activity of p53 in prognostically distinct renal tumors, including congenital mesoblastic nephroma, clear cell sarcoma of the kidney, renal cell carcinoma, anaplastic and classical Wilms tumor.

Recent Publications

Re, G.G., C. Waters, L. Poisson, M.C. Willingham, K. Sugamura, and A.E. Frankel, Interleukin 2 (IL-2) receptor expression and sensitivity to diphteria fusion toxin DAB389IL-2 in cultured hematopoietic cells, Cancer Research, 56:2590-2595, 1996.

Re, G.G., M.C. Willingham, R. el Bahtimi, N.A. Brownlee, D.J. Hazen-Martin, and A.J. Garvin, Anaplasia and drug selection-independent overexpression of the multidrug resistance gene, MDR1, in Wilms' tumor, Modern Pathology, 10:129-136, 1997.

Schandl, C.A., S. Li, G.G. Re, W. Fan, and M.C. Willingham, Mitotic chromosomal bcl-2. I. Stable expression throughout the cell cycle and association with isolated chromosomes, Journal of Histochemistry & Cytochemistry, 47:139-149, 1999.

Schandl, C.A., S. Li, G.G. Re, W. Fan, and M.C. Willingham, Mitotic chromosomal bcl-2. II. Localization to interphase nuclei, Journal of Histochemistry & Cytochemistry, 47:151-158, 1999.

Narayanan, B.A., O. Geoffroy, M.C. Willingham, G.G. Re, and D.W. Nixon, p53/p21 (WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells, Cancer Letters, 136:215-221, 1999.

Re, G.G., D.J. Hazen-Martin, R. El Bahtimi, N.A. Brownlee, M.C. Willingham, and A.J. Garvin, Prognostic significance of Bcl-2 in Wilms' tumor and oncogenic potential of Bcl-X(L) in rare tumor cases, International Journal of Cancer, 84:192-200, 1999.

Ma, J.X., D. Zhang, M. Laser, N.A. Brownlee, G.G. Re, D.J. Hazen-Martin, T.M. Redmond, and R.K. Crouch, Identification of RPE65 in transformed kidney cells, FEBS Letters, 452:199-204, 1999.
Delatte, S.J., D.J. Hazen-Martin, G.G. Re, J.R. Kelley, A. Sutphin, and E.P. Tagge. Restoration of p53 function in anaplastic Wilms' tumor. J Ped Surgery, 36:43-50, 2001.

Narayanan, B.A., and G.G. Re. IGF-2 down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid. Anticancer Research, 21:359-364, 2001.

Takahashi, M., Yang, X. J., Lavery, T. T., Furgew K. A., Williams B. O., Tretiakova, M., Montag A., Vogelzang N. J., Re, G. G., Garvin, A. J., Soderhall, S., Kagawa, S., Hazen-Martin, D., Nordenskjold, A., and Teh, B. T. Gene expression profiling of favorable histology wilms tumors and its correlationwith clinical features . Cancer research, 62: 6598-6606, 2002.

Brownlee, N. A., Hazen-Martin, D. J., Garvin, A. J., and Re, G.G. Functional and gene expression analysis of the p53 signaling pathway in Clear Cell sarcoma of the Kidney and Congenital Mesoblastic Nephroma. Ped Devel Pathol, 5: 257-268, 2002.

Narayanan, B. A., Narayanan, N. K., Re G. G., and Nixon, D. W. Differential expression of genes induced by resveratrol in LNCAP cells: p53-mediated molecular targets. Int J Cancer, 104: 204-212, 2003.

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