Toshihiko Kawamori, MD, Ph.D.
Assistant Professor
Pathology & Laboratory Medicine

EDUCATION

• MD, 1987, Gifu University School of Medicine
• Ph.D., 1996, Gifu University Graduate School of Medicine

RECENT (SELECTED) PUBLICATIONS

• Pettus, BJ., Kitatani, K., Chalfant, CE., Taha, T., Kawamori, T., Bielawski, J., Obeid, L., Hannun, YA. The cordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate. Mol. Pharmacol. in press.(abstract)
• Kawamori, T., Kitamura T, Watanabe K, Uchiya N, Maruyama T, Narumiya S, Sugimura T, Wakabayashi K. Prostaglandin E receptor subtype EP1 deficiency inhibits colon cancer development. Carcinogenesis, 26: 353-357, 2005. (abstract)
• Kawamori, T., Totsuka Y, Uchiya N, Kitamura T, Shibata H, Sugimura T, Wakabayashi K. Carcinogenicity of aminophenylnorharman, a possible novel endogenous mutagen, formed from norharman and aniline, in F344 rats. Carcinogenesis, 25: 1967-1972, 2004. (abstract)
• Shoji Y, Takahashi M, Kitamura T, Watanabe K, Kawamori T, Maruyama T, Sugimoto Y, Negishi M, Narumiya S, Sugimura T, Wakabayashi K. Down-regulation of prostaglandin E receptor subtype EP3 during colon cancer development. Gut, 53: 1151-1158, 2004. (abstract)
• Choudhury S, Zhang R, Frenkel K, Kawamori T, Chung FL, Roy R. Evidence of alterations in base excision repair of oxidative DNA damage during spontaneous hepatocarcinogenesis in Long Evans Cinnamon rats. Cancer Res., 63: 7704-7707, 2003. (abstract)
• Ochiai M, Ushigome M, Fujiwara K, Ubagai T, Kawamori T, Sugimura T, Nagao M, Nakagama H. Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Am. J. Pathol., 163: 1607-1614, 2003. (abstract)
• Kawamori T, Uchiya N, Sugimura T, Wakabayashi K. Enhancement of colon carcinogenesis by prostaglandin E2 administration. Carcinogenesis, 24: 985-990, 2003. (abstract)
• Furukawa F, Nishikawa A, Lee IS, Kanki K, Umemura T, Okazaki K, Kawamori T, Wakabayashi K, Hirose M. A cyclooxygenase-2 inhibitor, nimesulide, inhibits postinitiation phase of N-nitrosobis(2-oxopropyl)amino-induced pancreatic carcinogenesis in hamsters. Int. J. Cancer, 104: 269-273, 2003. (abstract)
• Osawa E, Nakajima A, Wada K, Ishimine S, Fujisawa N, Kawamori T, Matsuhashi N, Kadowaki T, Ochiai M, Sekihara H, Nakagama H. Peroxisome proliferators-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice. Gastroenterology, 124: 361-367, 2003. (abstract)
• Kawamori, T., Wakabayashi, K. COX-2 and prostanoid receptors, Good targets for chemoprevention. J. Envir. Pathol., Toxicol., Oncol., 21: 149-153, 2002. (abstract)
• Mutoh M, Watanabe K, Kitamura T, Shoji Y, Takahashi M, Kawamori T, Tani K, Kobayashi M, Maruyama T, Kobayashi K, Ohuchida S, Sugimoto Y, Narumiya S, Sugimura T, Wakabayashi K. Involvement of prostaglandin E receptor subtype EP4 in colon carcinogenesis. Cancer Res., 62: 28-32, 2002. (abstract)
• Takahashi M, Mutoh M, Kawamori T, Sugimura T, Wakabayashi K. Altered expression of b-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis. Carcinogenesis, 21: 1319-1327, 2000. (abstract)
• Watanabe K, Kawamori T, Nakatsugi S, Ohta T, Ohuchida S, Yamamoto H, Maruyama T, Kondo K, Ushikubi F, Narumiya S, Sugimura T, Wakabayashi K.Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis. Cancer Res., 59: 5093-5096, 1999. (abstract)
• Reddy BS, Kawamori T, Lubet RA, Steele VE, Kelloff GJ, Rao CV. Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process. Cancer Res., 59: 3387-3391, 1999. (abstract)
• Kawamori T, Lubet R, Steele VE, Kelloff GJ, Kaskey RB, Rao CV, Reddy BS. Chemopreventive effect of curcumin, a naturally-occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res., 59: 597-601, 1999. (abstract)
• Kawamori T, Rao CV, Seibert K, Reddy BS. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res., 58: 409-412, 1998. (abstract)

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