Welcome to the Department of Pathology
and Laboratory Medicine
The disciplines of Pathology and Laboratory
Medicine are uniquely positioned at the crossroads between basic
science research and the practice of clinical medicine, ready to use
new knowledge gleaned from scientific discovery for the diagnosis
and treatment of clinical disease states. Our abilities to detect even a single, malignant cell among
many benign ones are made possible by sophisticated instrumentation
with ultrahigh sensitivities and specificities, by state-of-the-art
DNA extraction methodologies developed by our research colleagues,
and by new tests such as in situ polymerase chain reactions,
fluorescence in situ hybridization, and the constantly evolving
fields of immunohistochemistry, flow cytometry, and molecular
pathology.
Anatomic, clinical and research pathologists
and hospital laboratorians can choose from a wide range of career
opportunities, from being the sole practitioner at a small community hospital, to being one of 200 in a large academic medical
center department.
Examples from our own hospital include people doing basic science
research, staffing a section of the clinical laboratory such as
Blood Bank, making diagnoses of malignancy at the time of operation
for a brain tumor, or teaching medical and graduate
students.Some of those
in our specialty have responsibilities which overlap multiple
different areas of the department and medical center.
The gold standard for the diagnosis of
malignancy is based upon a tissue sample obtained by a clinician
from their patient that is then processed and interpreted by a
surgical pathologist.No
treatment, whether it be surgery, radiation therapy or chemotherapy,
is given to the patient until a pathologist has rendered a malignant
diagnosis.The
pathologic classifications of malignancies are constantly under
evolution.We always
seek to further refine the classification systems to allow for an
even more precise diagnosis which helps our clinical colleagues
select a treatment modality tailored for a very specific disease
process.
We are “the doctor’s doctor.”We are involved in the treatment of every single patient in
our hospital.The
patient never sees or meets us, but we are as essential to their
recovery and survival as anyone else on the health care team.Come, join us on our mission to provide the very best patient
care possible for each and every patient.
Janice M. Lage, M.D.
Department Chairman
Pathology and Laboratory Medicine
Medical University of South Carolina