ORTHOPAEDIC RESEARCH LABORATORY
AT THE MEDICAL UNIVERSITY OF SOUTH CAROLINA

BOOKS

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PREFACE

Metabolic bone diseases, such as osteoporosis, osteomalacia, hyperparathyroidism, and Paget's disease, are usually associated with osteoporotic or soft skeleton, especially in the elderly patient. Orthopaedic procedures in elderly patients are costly and with the increasing age of the population these cost will continue to escalate. Great challenges are often encountered when internal fixation is needed for fractures or osteotomies to osteoporotic bone. This book is designed to carry basic and clinical essentials of osteoporosis and related orthopaedic issues on applied research and surgical treatment. Potential readers include orthopaedic surgeons, orthopaedic residents, orthopaedic researchers, fellows, and graduate students, as well as implant designers who work in orthopaedic departments or companies. The book will also be of interest to anyone working in the fields of clinical orthopaedics, orthopaedic research, or implant manufacture, and to internal medicine physicians who see osteoporotic patients. This is the first inclusive and organized reference book on orthopaedic relevance to osteoporotic conditions, a topic that has not been covered adequately by any existing books.

Yuehuei H. An, MD

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TABLE OF CONTENTS

PART I. BASIC SCIENCE AND CLINICAL ESSENTIALS

1. Etiology and Pathogenesis of Osteoporosis

2. Histomorphology of Osteoporotic Bone

3. Biomechanics of Osteoporotic Bone

4. Healing of Normal and Osteoporotic Bone

5. Animal Models of Osteoporosis

6. Radiology of Osteoporotic Bone

7. Densitometry of Osteoporotic Bone

8. Non-Invasive Analysis of Bone Mass, Structure, and Strength

 

PART II. OSTEOPOROTIC FRACTURE

9. Osteoporotic Fractures &endash; Epidemiology, Risk Factors, and Prevention

10. Biochemical Markers Before and After Osteoporotic Fractures

11. Osteopenia and Osteoporosis - Muscle-Bone Interactions, Absorptiometry, Safety Factors, and Fracture Risk

12. Post-Fracture Osteopenia and Its Etiology

13. Identification of Fragility Fracture Patients in a Fracture Clinic Setting

 

PART III. SURGICAL MANAGEMENT OF OSTEOPOROTIC FRACTURES

14. Reactions of Normal and Osteoporotic Bone to Fixation Devices

15. Current Concepts of Internal Fixation in Osteoporotic Bone

16. Cement Augmentation of Internal Fixation Devices in Osteoporotic Bone

17. Management of Osteoporotic Fractures of Upper Extremities

18. Management of Osteoporotic Fractures of Lower Extremities

 

PART IV. SURGICAL MANAGEMENT OF OSTEOPOROTIC SPINE

19. Challenges of Internal Fixation in Osteoporotic Spine

20. Biomechanics of Interbody Fusion in Osteoporotic Spine

21. Investigations on Bone Cement for Vertebroplasty

22. Clinical Application of Vertebroplasty and Kyphoplasty

 

PART IV. JOINT PROSTHESIS AND OSTEOPOROSIS

23. Joint Replacement in Osteoporotic Bone

24. Transient Regional Osteoporosis in Arthrosis and after Arthroplasty

25. Bone Ingrowth to Prostheses in Osteoporotic Bone

26. Periprosthetic Fractures due to Osteoporotic Conditions

27. The Prevention of Periprosthetic Osteopenia

 

PART V. SECONDARY OR OTHER FORM OF OSTEOPOROSIS

28. Osteoporosis in Rheumatoid Arthritis

29. Osteoporosis and Related Fractures Caused by Immobilization

30. Relationship between Osteoporosis and Osteoarthritis

 

PART VI. PREVENTION AND MANAGEMENT OF OSTEOPOROTIC CONDITION

31. Care of Osteoporotic Patients in Orthopaedic Clinics

32. Accelerating Bone Healing of Osteoporotic Fractures

33. Exercise for Prevention of Osteoporotic Fractures

34. Pharmacological Management of Osteoporotic Conditions