(All images or drawings are generated by MUSC Orthopaedic Research Lanboratory)
Figure 1. Nude mouse subcutaneous injection or implantation sites for testing tissue genesis.
Figure 2. Nude mouse subcutaneous implantation of an undecalcified material for osteogenesis.
Figure 3. Left: Nude mouse subcutaneous injection osteogenesis
model. Right: A histological image showing bone nodule formed
4 weeks after injection a collagen gel containing Ne-Osteo (a mixture
of BMPs from Sulzer Biologics) in rat subcutaneous tissue.
Figure 4. Nude mouse subcutaneous osteogenesis model (Bone formed in titanium foam coated with hydroxyapatite)
.
Figure 5. Nude mouse kidney capsule model. (A) Neocartilage formed
12 weeks after injection
of bovine chondrocytes mixed in glucosamine gel. (B) Histology shows
typical hyaline cartilage.
(C) Some areas in the nodule show endochondral ossification (Black
arrows).
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