Bone Defect Models

(All images or drawings are generated by MUSC Orthopaedic Research Lanboratory)


 

Figure 1. Rabbit distal femoral drill hole defect model through a lateral approach. (A) Line drawing illustrates the
model; (B) 12 weeks after grafting with demineralized bone matrix; (C) 12 weeks after grafting with Collagraft.

Figure 2. Rabbit radial defect model (Rabbits need to be more than 8 months old with closed growth plates).

Figure 3. Rabbit calvarial defect models. (A) On critical size defect, 15 mm in diameter.
(B) Four small defects, 6 mm in diameter, for comparing different grafts.

Figure 4. Rabbit calvarial defect model repaired with hydroxyapatite-collagen sponge impregnated with TGF-b.

Figure 5. Diaphyseal weight-bearing bone segmental defects in rabbit tibia (A), sheep tibia (B), and canine femur (C).

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