Subcutaneous Implantation Model for Testing Biocompatibility

(All images or drawings are generated by MUSC Orthopaedic Research Lanboratory)


 

Figure 1. Sample disks can be implanted into the rat or rabbit subcutaneous
tissue. Samples can also be implanted into the back or thigh muscles of the animals.

Figure 2. Explantation image shows that a small titanium sample disk
(1.0 mm in thickness and 10 mm in diameter) in rat subcutaneous tissue.

Figure 3. Explantation image shows that 6 small plastic sample disks
(0.5 mm in thickness and 10 mm in diameter) in rabbit subcutaneous tissue.

Figure 4. Histologic image shows a fibrous capsule formed around a titanium implant.

 

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