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Lankupalle Jayanthi, Ph.D.
Professor Department of Physiology & Neuroscience,
Medical University of South Carolina, Charleston, SC.
Phone: (843) 792-8542
Fax: (843) 792-1066
Email: jayanthi@musc.edu
Education:
B.Sc. (BS) Chemistry, Physics and Zoology, 1980-1983, University of Madras, Madras, India;
M.Sc. (MS) Biochemistry, 1983-1985, Sri Venkateswara University, Tirupati, India.;
Ph.D. Biochemistry, 1986-1992, Christian Medical College Hospital, Vellore, India.
Research Interests:
Functional regulation of monoamine transporters: relevance to fetal development.
Selected Publications:
Jayanthi, L.D., Prasad, P.D., Ramamoorthy, S., Mahesh, V.B., Leibach, F.H. and Ganapathy, V. (1993). Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter. Biochemistry. 32: 12178-12185.
Jayanthi, L.D., Ramamoorthy, S., Mahesh, V.B., Leibach, F.H. and Ganapathy, V. (1994). Cocaine sensitive sigma receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells. Endocrinology. 136: 924-932.
Ramamoorthy, J.D, Ramamoorthy, S., Leibach, F.H. and Ganapathy, V. (1995). Human placental monoamine transporters as targets for amphetamines. American Journal of Obstetrics and Gynecology. 173:1782-1787.
Fritz, J.D., Jayanthi, L.D., Thoreson, M.A. and Blakely, R.D. (1998). Cloning and chromosomal mapping of the murine norepinephrine transporter. Journal of Neurochemistry. 70: 241-2251.
Jayanthi, L.D., Apparsundaram, S., Malone, M.D., Ward, E., Miller, D.E., Eppler, M., Blakely, R.D. (1998). The caenorhabditis elegans gene T23G5.5 encodes an antidepressant and cocaine sensitive dopamine transporter. Molecular Pharmacology. 54: 601-609.
Galli, A., Jayanthi, L.D., Ramsey, S., Fremeau, R.T. and DeFelice, L.J. (1999) Proline and pipecolic acid induced des-tyrosyl enkaphalin-sensitive currents in HEK-293 cells transfected with rat proline transporter. Journal of Neuroscience 19: 6290-6297.
Jayanthi, L.D., Wilson, J.J., Fremeau, R.T and DeFelice, L.J. (2000) The role of calcium in the regulation of the proline transporter. British Journal of Pharmacology.129: 465-470.