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MCBP Past Seminars
This is a collection of past seminars held by the MCBP Program.
Thursday External Seminar Series Calendar
Room 125 - Gazes Conference Room - 4:00 pm
Gazes Cardiac Research Institute/Strom Thurmond Building


Fall 2011
January 6, 2011

Randy R. Brutkiewicz, Ph.D.
Professor and Assistant Dean of Faculty Affairs
and Professional Development
Indiana University School of Medicine

Title: “Regulation of Antigen Presentation by Cell Signaling Pathway”

Host: Dr. Azizul Hague
Sponsor: Biochemistry
January 13, 2011

No Seminar

Host:
Sponsor: Biochemistry
January 20, 2011

Gustavo W. Leone, Ph.D.

Associate Professor,
Molecular Virolgy, Immunology, & Medical Genetics
Human Cancer Genetics Program
Ohio State University, College of Medicine

Title: “PTEN & p53 in the Tumor Microenvironment: Out in the Neighborhood”

Host: Dr. Ogretmen
Sponsor: Biochemistry
January 27, 2011

Seminar Cancelled

 
February 3, 2011

Seminar Cancelled

 
February 10, 2011

Richard A. Cerione, Ph.D.

Professor of Pharmacology
Department of Molecular Medicine
College of Veterinary Medicine, Cornell University

Title: "Cdc42: Some New and Unexpected Discoveries"

Host: Dr.Yusuf Hannun
Sponsor: Biochemistry
February 17, 2011


Federico Gonzalez-Fernandez, M.D., Ph.D.

Professor of Ophthalmology & Pathology
Ross Eye Institute, State University of NY

Title: “Interphotoreceptor retinoid-binding protein (IRBP) - an old gene for new eyes”

Host: Dr. Yiannis Koutalos
Sponsor: MCBP
February 24, 2011

Jia L. Zhuo, MD, PhD

Professor of Pharmacology and Medicine
Laboratory of Receptor and Signal Transduction
Department of Pharmacology & Toxicology
Division of Nephrology
Department of Internal Medicine
The University of Mississippi Medical Center

Title: “Intracrine Renin-antiotensin System: A New Paradigm in Cardiovascular and Renal Control”

Host: Drs. Fitzgibbon and
Morinelli

Sponsor: MCBP

March 3, 2011


Charlie Boone, Ph.D.

Professor
Banting and Best Department of Medical Research
University of Toronto
Toronto, Canada

Title: “The Genetic Landscape of a Cell”

Host: Dr. Ashley Cowart
Sponsor: Biochemistry
March 10, 2011


Eva M. Mezey, M.D., Ph.D.

NIH, NIDCR
Bethesda, MD

Title: "Immunosupression by bone marrow derived stromal cells"

Host: Dr. Monika Gooz
Sponsor: MCBP
March 17, 2011

Webster Cavenee, Ph.D.

Professor of Medicine and Cell & Molecular Medicine
Cancer Biology Program
Director, Ludwig Institute for Cancer Research
University of California, San Diego

Title: “Cell Intrinsic and Extrinsic Effects of Cell Signaling: Implications for Tumor Population Dynamics"

Host: Dr. Dennis Watson
Sponsor: MCBP
March 24, 2011

Dr. Natasha Kyprianou

James F. Hardymon Chair of Urology Research
Professor of Surgery/Urology
Professor of Molecular and Cellular Biochemistry
Professor of Pathology and Laboratory Medicine

Title: “TGF-beta Signaling in Prostate Cancer”

Host: Drs. Jim Norris/Christina Voelkel-Johnson

Sponsor: Micro and Immunol

March 31, 2011

Matthew (Mengsheng) Qiu, Ph.D.

Professor & Distinguished Scholar
Anatomical Sciences & Neurobiology
University of Louisville

Title: "Origin and molecular specification of oligodendrocytes in the Spinal Cord”

Host: Narayan Bhat
Sponsor: MCBP
April 7, 2011

Seminar Cancelled

Host:
Sponsor: Biochemistry
April 14, 2011

Rima Rosen, Ph.D.

Professor, Department of Human Genetics,
Vice Principal for Research & International Relations
McGill University, Montreal, Quebec, Canada

Title: "Genetic and Nutritional Deficiencies in Folate Metabolism: Impact on Complex Traits"

Host: Natalia Krupenko
Sponsor: Biochemistry
April 21, 2011

Roderick Dashwood, Ph.D.

Oregon State University
PI & Director, Cancer Chemoprotection Program
Linus Pauling Institute
Professor, Department of Environmental and Molecular Toxicology
Corvallis, OR

Title: "Metabolism as a key to HDAC inhibition by dietary chemoprotective agents"

Host: Dr. Michael Wargovich
Sponsor: Pharmacology
  APRIL 27, 2011: CLASSES END  
April 28, 2011

Seminar Cancelled

 
May 5, 2011 Seminar Cancelled  
May 12, 2011 Seminar Cancelled  
May 19, 2011

Adrian Lee, Ph.D.

University of Pittsburgh Schools of the Health Sciences
Visiting Professor, Department of Pharmacology Chemical Biology
Director, Women’s Cancer Research Center
Pittsburg, PA

Title: “Targeting IGF-IR in breast cancer”

Host: Dr. Carola Neumann
Sponsor: Pharmacology
May 26, 2011 Seminar Cancelled  
June 2, 2011

Vassiliki Karantza, M.D., Ph.D.

UMDNJ-Robert Wood Johnson Medical School
The Cancer Institute of New Jersey
New Brunswick, NJ

Title: TBA

Host: Dr. Carola Neumann
Sponsor: Pharmacology
Fall 2010
September 16, 2010 Sumanth D. Prabhu, M.D.
Professor and University Scholar
Division of Cardiovascular Medicine
University of Louisville Health Sciences Center

Title: “Inflammatory Pathways in Heart Failure”

Host: Dr. Francis G. Spinale
Sponsor: MCBP

September 23, 2010 Yusen Liu, PhD
Associate Professor of Pediatrics (with tenure)
Center for Perinatal Research
The Research Institute at Nationwide Children’s Hospital
Department of Pediatrics
The Ohio State University College of Medicine

Title: “MAP Kinase Phosphatase-1, a Critical Regulator of Innate Immunity and Beyond”

Host: Dr. Keith L. Kirkwood
Sponsor: Microbiology/Division of Basic Sciences

September 30, 2010 Alexander Tropsha, Ph.D.
Professor and Chair of Medicinal Chemistry and Natural Products
UNC Chapel Hill School of Pharmacy
Chapel Hill, North Carolina

Title: “Chemocentric Informatics: Computational Analysis of Integrated Chemical-Biological Data Sources to Enable Molecular Probe and Drug Discovery”

Host: Dr. Yuri Peterson
Sponsor: Lanier NSF Grant

October 7, 2010 Dr. Bryan R. Cullen
James B. Duke Professor
Department of Molecular Genetics and Microbiology Director
Duke University Center for Virology
Duke University Medical Center – Durham, North Carolina

Title: “Viruses, microRNAs and RNA interference.”

Host: Dr. Mirko Hennig
Sponsor: Biochemistry/Division of Basic Sciences

October 14, 2010 Paul D. Roepe, Ph.D.
Professor and Chair of Chemistry
Professor of Biochemistry and Molecular Biology and Tumor Biology
Lombardi Cancer Center
Georgetown University

Title: "Quinoline Antimalarial Drug Resistance"

Host: Dr. Donald Menick
Sponsor: MCBP

October 21, 2010 Ron R. Kopito, Ph.D.
Professor Stanford University
Department of Biological Sciences
Stanford University – Stanford, California

Title: "Quality control on the protein assembly line"

Host: Dr. Stephen Lanier
Sponsor: MCBP

October 28, 2010 TBA

 

November 4, 2010 Student Research Day – No Seminar

 

November 11, 2010 TBA

Host: Craig Crosson 
Sponsor: MCBP

November 18, 2010 Dr. Fred Marshall Winston
John Emory Andrus Professor of Genetics
Harvard Medical School
Boston, MA

Title: "Factors that control transcription and chromatin structure in yeast”

Host: Dr. Deepak Bastia 
Sponsor: Biochemistry/Division of Basic Sciences

November 25, 2010 Happy Thanksgiving!

 

December 2, 2010 Leslie B. Gordon, M.D., Ph.D.
Staff Scientist
Children’s Hospital Boston
Department of Anesthesia, Boston, MA

Title: “Hutchinson-Gilford Progeria Syndrome: A New Avenue for Cardiovascular and Aging Research Through Rare Disease Discoveries”

Host: Dr. Bryan  P. Toole
Sponsor: MCBP

December 9, 2010 Dr. Christopher M. Counter
Associate Professor
Department of Pharmacology and Cancer Biology
Duke University Medical Center

Title: "Oncogene Addiction: NO Way”

Host: Dr. Besim Ogretman
Sponsor: Biochemistry/Division of Basic Sciences

December 16, 2010

Ramon Parsons, M.D., Ph.D.
Avon Professor of Pathology & Medicine Leader
Breast Cancer Program Institute for Cancer Genetics
Herbert Irving Comprehensive Cancer Center Columbia University New York, NY

Title: “The PTEN Pathway and Cancer”

Host: Dr. Carola A. Neumann
Sponsor: Biochemistry/Division of Basic Sciences

Spring 2010
January 21, 2010 Erica A. Golemis, Ph.D.
Senior Member
Fox Chase Cancer Center
Philadelphia, PA

Title: “Nedd9 and Aurora-A: integrating multiple signaling pathways in Cancer”

Host: Dr. Steven Rosenzweig
Sponsor:  MCBP

January 28, 2010

Harold Ray (Skip) Garner, Jr., Ph.D.
Executive Director
Virginia Bioinformatics Institute
Virginia Tech

Title:  “Global germline and tumor microsatellite patterns are putative cancer biomarkers, and can be used to identify individual diagnostic loci”

Host:  Dr. Jim Zheng
Sponsor:  Biochemistry
February 4, 2010

John Condeelis, Ph.D.
Judith & Burton P. Resnick Chair in Translational Research Professor and Co-Chair, Anatomy & Structural Biology Co-Director, Gruss Lipper Biophotonics Center Scientific Director, Analytical Imaging Facility Director, Tumor Microenvironment and Metastasis Program Albert Einstein Cancer Center Albert Einstein College of Medicine

Title: “Microenvironments of metastasis:  Insights derived by multiphoton imaging”

Host:   Dr. Steven Rosenzweig
Sponsor: MCBP
February 11, 2010

Everett C. Pesci, Ph.D.
Professor from the Department of Microbiology and Immunology
Brody School of Medicine
East Carolina University

Title:  “Quinolone Signaling by Pseudomonas aeruginosa

Host:  Dr. Yong-Mei Zhang
Sponsor: Biochemistry
February 18, 2010

Patrick J. Stover, Ph.D.
Professor & Director
Division of Nutritional Sciences
Cornell University            
Ithaca, NY

Title:  “Nuclear Folate Metabolism and Folate-associated Cancers and Developmental Anomalies”

Host:  Dr. Krupenko
Sponsor:  Biochemistry
February 25, 2010 Mario Delmar, M.D., Ph.D.
Frank Norman Wilson Professor of Cardiovascular Medicine.
Professor of Internal Medicine and of Molecular and Integrative Physiology.
Director of Basic Science, Division of Cardiovascular Medicine.
Co-Director, Center for Arrhythmia Research.
University of Michigan

Title:  "Sodium channels, gap junctions and desmosomes: Tres Amigos at the Intercalated Disc"

Host:  Dr. Robert Gourdie
Sponsor:  MCBP
March 4, 2010

Jim R. Davie, Ph.D.
Acting Associate Director -Institute of Cell Biology
Professor, Dept. of Biochemistry and Molecular Biology
MRC Senior Scientist
University of Manitoba
                          
Title:  “Protein kinase CK2 phosphorylation of HDAC2: Role in complex formation and genome location”

Host:  Dr. Donald Menick
Sponsor:  MCBP
March 6 - 14, 2010 Spring Break  
March 18, 2010 No Seminar  
March 25, 2010

Michael W. McBurney, Ph.D.
Program Director, Cancer Therapeutics, Ottawa Hospital Research Institute
Professor of Medicine and Biochemistry, Microbiology and Immunology,
University of Ottawa

Title:  "Physiological Deficits in SirT1-null Mice – the role of sirtuins in aging"

Host:  Dr. Donald Menick
Sponsor: MCBP

April 1, 2010 No Seminar  
April 8, 2010

Tamara Lea Doering, M.D./Ph.D.
Washington University School of Medicine
Division of Biology and Biomedical Sciences
Department of Molecular Microbiology
St. Louis, MI

Title:  “How sweet it is!  Capsule synthesis in the pathogenic fungus Cryptococcus neoformans

Host:  Dr. Maurizio Del Poeta 
Sponsor:  Biochemistry & Burroughs Wellcome Fund
April 15, 2010

Bradley K. Yoder, Ph.D.
Professor of Cell Biology
University of Alabama Birmingham

Title:  “Emerging Role of Cilia in Development and Disease”

Host:  Dr. Courtney Haycraft
Sponsor:  MCBP
April 22, 2010

Jack D. Keene, Ph.D.
James B. Duke Professor
Department of Molecular Genetics and Microbiology
Duke University Medical Center

Title:  "Dynamic Post-transcriptional RNA Operons and Regulons"
Host:  Dr. Tilman Heise
Sponsor:  Biochemistry
April 29, 2010

W. Daniel Stamer, Ph.D.
Professor and Associate Head of Ophthalmology and Vision Science
Professor of Pharmacology & Physiology
The University of Arizona

Title:  “Biomechanical and Pharmacological Regulation of Conventional Outflow”

Host: Dr. Craig Crosson
Sponsor:  MCBP
May 6, 2010 Paul Dent, Ph.D.
Professor of Biochemistry & Molecular Biology
Virginia Commonwealth University School of Medicine

Title:  “Sorafenib and HDAC inhibitors synergistically interact to kill GI tumor cells through ceramide dependent CD95 activation”

Host:  Dr. Christina Voelkel-Johnson
Sponsor:  Microbiology & Immunology
May 13, 2010

Nicholas Tonks, Ph.D.
Professor, Cold Spring Harbor Laboratory
Cold Spring Harbor, New York

Title:  “Signal transduction from a protein tyrosine phosphatase perspective”

Host:  Dr. Carola A. Neumann
Sponsor:  Pharmacology
May 20, 2010

Gregg Silverman, M.D.
Professor of Medicine
Director, Laboratory of B cell Immunobiology
UCSD School of Medicine

Title:  "The dual inhibitory receptor hypothesis: Autoantibodies and immune homeostasis"

Host: Dr. Stephen Tomlinson
Host: Dr. Gary Gilkeson
Sponsor: Microbiology & Immunology
May 27, 2010

TBA

Title: TBA

Host: TBA
Sponsor: Pharmacology
June 10, 2010 Thomas L. Clemens
Department of Orthopaedic Surgery
Johns Hopkins University
Editor-in-Chief, Journal of Bone and Mineral Research

Title: "Insulin signaling in osteoblasts regulates bone and body composition".

Host:  Lauren Ball
Sponsor: Microbiology & Immunology
June 17, 2010

Kamal Khanna, Ph.D.
Assistant Professor
University of Connecticut Health Center                               
Department of Immunology                                                                                       

Title:  “Visualizing endogenous CD8 T cell immune response to infection: important role of Sphingosine-1-phosphate receptors"

Host: Dr. Shikhar Mehrotra
Sponsor: Microbiology & Immunology
Spring 2009
January 15, 2009 Paul D. Drew, Ph.D.
Professor Neurobiology and Developmental Sciences
Director Cellular and Molecular Neuroscience Center
University of Arkansas for Medical Sciences

Title: "Peroxisome Profilferator-Activated Receptors: Potential Modulators of Multiple Sclerosis"
Host: Dr. Inderjit Singh
Sponsor: MCBP Program
January 22, 2009 Nahum Sonenberg, Ph.D. Host: Dr. Tilman Heise
Professor Biochemistry and McGill Cancer Centre Sponsor: Biochemistry
Rosalind and Morris Goodman Cancer Centre
McGill University

Title: "Translation control in cancer and miRNA function"
 
January 29, 2009 Michael Rosol, Ph.D.
Assistant Professor of Radiology
Medical University of South Carolina

Title: "Dynamic tracking of human hematopoietic stem cells in mice"
Sponsor: MCBP
February 5, 2009 Bruce D. Carter, Ph.D.
Professor of Biochemistry
Vanderbilt University Medical Center

Title: "Mechanisms of neuronal apoptosis and phagocytic clearance in the developing of peripheral nervous system"
Host: Dr. Hiroko Hama
Sponsor: Biochemistry
February 12, 2009 Kenneth D. Philipson, Ph.D.
Distinguished Professor of Physiology & Medicine
David Geffen School of Medicine
University of California, Los Angeles

Title: "Cardiac Sodium-Calcium Exchange: A Tale of Two Sites"
Host: Dr. Donald R. Menick
Sponsors: MCBP & Cardiovascular Training Grant
February 19, 2009 Roel van der Veen, Ph.D.
Associate Professor of Neurology
University of Southern California, Keck School of Medicine

Title: "Innate myeloid cells regulate T cell activity through interacting nitric oxide and Superoxide"
Host: Dr. Inderjit Singh
Sponsor: MCBP Program
February 26, 2009 Alexadra Lucas, M.D.
Section Head Vascular Research
University of Florida

Title: "The Serpin Saga – Treatment of Inflammation in Vascular Disease"
Host: Dr. Francis Spinale
Sponsor: MCBP & Cardiovascular Training
Grant
March 5, 2009 Kathleen L. Gould, Ph.D.
Professor of Cell & Developmental Biology
HHMI Investigator
University of Southern California

Title: "Split decisions: regulating the end of the cell cycle"
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
March 7-15, 2009 Spring Break  
March 19, 2009 TBA  
March 26, 2009 David Giedroc, Ph.D.
Professor
Department of Chemistry
Indiana University

Title: "RNA structural and functional determinants of the 5’ and 3’ tips of the coronavirus genome"
Host: Dr. Mirko Henning
Sponsor: Biochemistry
April 2, 2009 TBA  
April 9, 2009 William A. Dunn, Jr., Ph.D.
Professor
Department Anatomy and Cell Biology University of Florida College of Medicine
Gainesville, Florida

Title: "Endogenous and Exogenous Regulation of Pexophagy and Autophagy"
Host: Dr. John Lemasters
Sponsor: College of Pharmacy
April 16, 2009 W. Gray Jerome, Ph.D., FAHA
Pathology
Vanderbilt University Medical Center
U2206 MCN
1161 21st Ave., South
Nashville, TN 37232-2561
615-322-5530 jay.jerome@vanderbilt.edu

Title: "The Role of Lysosomes in Atherosclerosis"
Host: Dr. Samar Hammad
Sponsor: MCBP
April 23, 2009 Stuart A. Aaronson, M.D.
Professor and Chairman
Department of Oncological Sciences
Mount Sinai School of Medicine

Title: "Translating Cancer Gene Discovery to the Clinic"
Host: Dr. Dennis Watson
Sponsor: MCBP
April 30, 2009 TBA  
May 7, 2009 Warren D. Kruger, Ph.D.
Senior Member
Popular Science Division
Fox Chase Cancer Center

Title: "How to Fix a Broken Protein"
Host: Dr. Sergey Krupenko
Fall 2008
September 4, 2008 Robert C. Dickson, PhD
Professor of Molecular and in
Cellular Biochemistry Lipidomics & Pathobiology
University of Kentucky

Title: Do Sphingolipids Play Roles in Regulating Lifespan in Yeast?
Host: Dr. Ashley Cowart
Sponsor: COBRE
September 11, 2008 Robert M. Gemmill, PhD
Melvyn Berlinsky Chair in Cancer Research
Prof. of Medicine, Hematology/Oncology Division
Medical University of South Carolina

Title: Linkage of Lipid Homeostasis with Protein Translation through the TRC8/RNF139 Kidney Cancer Tumor Suppressor
 
September 18, 2008 Ward B. Watt, PhD
Professor of Biology
Trustee and President, California Academy of Sciences
Department of Biological Sciences
Stanford University
Sanford, California

Title: Evolution of Protein Structure and Function:
From Molecules to Ecosystems
Host: Dr. Christopher Davies
Sponsor: MCBP Program
October 2, 2008 Wendy Bollag, Ph.D., Professor
Institute of Molecular Medicine and Genetics
Medical College of Georgia
Augusta, Georgia

Title: Priming of Aldosterone Secretion:
Phospholipase D and A Type of Cellular Memory
Host: Dr. Tom Morinelli
Sponsor: MCBP Program
October 9, 2008 Jakob Vinten-Johansen, MS, PhD, Professor
Division of Cardiothoracic Surgery
Department of Surgery
Associate Professor of Physiology
Emory University School of Medicine
Director, Cardiothoracic Research Laboratory
Carlyle Fraser Heart Center
Emory Crawford Long Hospital

Title: Cardiac Self-Defense 101: Innate Cardioprotection from Ischemia- Reperfusion Injury with Postconditioning
Host: Dr. Frank G. Spinale
Sponsor: MCBP Program
October 16, 2008

Wonhwa Cho, PhD Distinguished Professor of Chemical Biology
Department of Chemistry
University of Illinois at Chicago

Title: Spatiotemporal Regulation of Cellular Processes by Lipids and Lipid-binding Proteins: Proteomics and Single Molecule Studies

Host: Dr. Yusuf Hannun
Sponsor: Biochemistry
October 23, 2008 Michel Bouvier PhD, FCAHS Host: Dr. Stephen Lanier
Professeur Departement de Biochimie Sponsor: MCBP Program
Institut de Recherche en Immunologie et Cancer
Directeur Groupe de Recherche Universitaire sur le Médicament
Toronto, Canada

Title: Molecular Basis of G Protein-coupled Receptors Functional Selectivity; Linking Ligand-based Signaling to Specific Protein Complex Assemblies
 
October 30, 2008 Thomas Michel, MD, PhD
Dean for Education, Harvard Medical School
Professor of Medicine and Biochemistry
Federman Chair in Medical Education
Harvard University
Senior Physician in Cardiovascular Medicine
Brigham and Women’s Hospital

Title: Nitric Oxide Synthases and Cardiovascular Signal Transduction
Host: Dr. Yusuf Hannun
Sponsor: Biochemistry
November 6, 2008 NO SEMINAR Student Research Day
(November 7, 2008)
 
November 13, 2008 Jonathan D. Dinman, PhD, Professor
Department of Cell Biology & Molecular Genetics
University of Maryland
College Park, Maryland

Title: Programmed Ribosomal Frameshifting:
It’s Not Just for Viruses Anymore
Host: Dr. Mirko Hennig
Sponsor: Biochemistry
November 20, 2008 Yuan Liu, PhD, Assistant Professor
Department of Biology
Georgia State University
Atlanta, Georgia

Title: Modulating Leukocyte Inflammatory Responses by Cell Surface Receptors
Host: Dr. Titus Reaves
Sponsor: MCBP Program
December 4, 2008 TBA  
December 11, 2008 Jerard Hurwitz, Ph.D.
Sloan-Kettering Institute Professor
Cornell University Medical College
Head, William Randolph Hearst Laboratory
Of Radiation Biology
Memorial Sloan-Kettering Cancer Center
New York, New York

Title: TBA
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
Spring 2008
January 10, 2008 Sam W. Lee, Ph.D.
Associate Professor
Harvard Medical School
Associate Director, Cutaneous Biology Research Center
Massachusetts General Hospital
Boston, Massachusetts

Title: Cell Fate Decision by Tumor Suppressor p53: Live or Die
Host: Dr. S. Krupenko
Sponsor: Biochemistry
January 17, 2008 G. David Roodman, MD, PhD
Professor of Medicine and
Division of Hematology and Oncology Pediatrics
University of Pittsburgh

Title: Novel Targets for Treating Myeloma Bone Disease
Host: Dr. Sakamuri V. Reddy
Sponsor: MCBP Program
January 24, 2008 Susan R. George, MD, FRCP, FACP
Professor of Medicine and Pharmacology
University of Toronto
Canada Research Chair in Molecular Neuroscience
Head, Molecular Pharmacology
Centre for Addiction and Mental Health
Endocrinologist, University Health Network

Title: Homo- and Hetero-oligomerization of G Protein Coupled Receptors: Novel Insights into Receptor Trafficking and Function
Host: Dr. Steve Lanier
Sponsor: MCBP Program
January 31, 2008 Robert A. Sclafani, Ph.D.
Professor and Interim Chairman
Biochemistry and Molecular Genetics
University of Colorado Health Sciences Center

Title: Regulation of Genomic Replication and Fidelity by Cdc7-Dbf4 Kinase
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
February 7, 2008 ogy Transfer Ryan N. Fiorini, M.B.A., Ph.D.
Licensing and Technology Analyst
MUSC Foundation for Research Development

Title: The Basics of Intellectual Property and Technol
 
February 14, 2008 Douglas C. Eaton, Ph.D.
Distinguished Professor and Chairman
Department of Physiology
Director, Center for Cell & Molecular Signaling
Emory University Medical School
Atlanta, Georgia

Title: Direct Activation of the IGF-1 Receptor by Aldosterone
Host: Dr. Darwin Bell
Sponsor: MCBP/ and Division of Nephrology
February 21, 2008 No Seminar  
February 28, 2008 Maria Joan Curcio, Ph.D.
Professor and Research Scientist
Wadsworth Center
Developmental Genetics and Bioinformatics
New York State Department of Health

Title: Yeast Retrogenomics: The Role of Retrotransposons and Retrosequences in Genome Restructuring
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
March 6, 2008 Dean’s office uses Room 125  
March 13, 2008 SPRING BREAK  
March 20, 2008 Cheryl A. Kitt, Ph.D.
Deputy Director of the Center for
Scientific Review
National Institutes of Health

Title: Enhancing Peer Review: NIH/CSR Challenges
Host: Dr. Stephen M. Lanier
Sponsor: MCBP Program
March 27, 2008 No Seminar  
April 3, 2008 Raghu Kalluri, Ph.D.
Associate Professor of Medicine
Harvard Medical School and
Beth Israel Deaconess Medical Center
Chief, Division of Matrix Biology
Boston, Massachusetts

Title: Tumor Microenvironment in Cancer Progression and Metastasis
Host: Student, Tejas Tirodkar
Sponsor: Dean’s Seminar Series Speaker College of Graduate Studies
April 10, 2008 John D. York, Ph.D.
Investigator, Howard Hughes Medical
Institute
Department of Pharmacology and
Cancer Biology
Duke University Medical Center
Durham, North Carolina

Title: An Inositol Phosphate Code Essential for Development and Cellular Adaptation
Host: Dr. Besim Ogretmen
Sponsor: Biochemistry
April 17, 2008 Jay A. Tischfield, Ph.D.
Duncan and Nancy MacMillan Professor
of Genetics and Chair
Department of Genetics
Nelson Biological Labs
Rutgers University
Piscataway, New Jersey

Title: DNA Repair and Recombination on Somatic versus Embryonic Stem Cells
Host: Dr. Donald R. Menick
Sponsor: MCBP Program
April 24, 2008 Suneel S. Apte, M.B.B.S., D. Phil.
Staff
Department of Biomedical Engineering
The Cleveland Clinic Foundation
Cleveland, Ohio

Title: Cooperative Developmental Roles of ADAMTS Proteases
Host: Dr. Christine Kern
Sponsor: MCBP Program
May 1, 2008 Jeffery Twiss, M.D., Ph.D.
Head, Neuroscience Research Laboratory
Department of Biomedical Research
Nemours Biomedical Research
Alfred I. duPont Hospital for Children
Wilmington, Delaware

Title: Regulating Neuronal mRNA Transport – A New Route for Neural Repair
Host: Dr. Donald R. Menick
Fall 2007
September 13, 2007 Walter Holleran, PharmD
Associate Adjunct Professor
Dermatology and Pharmaceutical Chemistry
Member, UCSF Comprehensive Cancer Center
University of California at San Francisco
San Francisco, California

Title: "Skin Sphingolipids: Metabolism, Transport & Functions"
Host: Dr. Hiroko Hama
Sponsor: Biochemistry
September 20, 2007 Rosemarie M. Booze, Ph.D.
Professor and Bicentennial Endowed Chair
of Behavioral Neuroscience
University of South Carolina
Columbia, South Carolina

Title: "HIV and Drugs of Abuse: Neurodegenerative Mechanisms"
Host: Dr. Inderjit Singh
Sponsor: MCBP Program
September 27, 2007 Michael J. Wargovich, Ph.D.
Professor of Cell and Molecular Pharmacology
Director, Cancer Chemoprevention Program
Medical University of South Carolina

Title: "Prevention of Colon Cancer: Inflammation and Traditional Medicine"
 
October 4, 2007 Vytas A. Bankaitis, PhD
Professor and Chair Dr. Yusuf Hannun
Department of Cell & Developmental
Biology
University of North Carolina
School of Medicine
Chapel Hill, North Carolina

Title: "A High Resolution View of the Collaboration Between
Phosphatidylinositol Transfer Proteins and Lipid Kinases:
New Paradigms for the Regulation of Phosphoinositide Signaling"
Host: Dr. Besim Ogretmen
Sponsor: Biochemistry
October 11, 2007 Robert Skoff, PhD
Professor of Anatomy
Wayne State University
Detroit, Michigan

Title: "Sex Hormones: What they do to your Oligodendrocytes"
Host: Dr. Inderjit Singh
Sponsor: MCBP Program
October 18, 2007 Sheldon E. Litwin, M.D.
Professor Internal Medicine/Cardiology
Director, Cardiology Fellowship Cardiovascular Training Grant
Director of Cardiovascular Imaging
University of Utah Hospital
Salt Lake City, Utah

Title: "Obesity and the Heart: New Perspectives on a New Epidemic"
Host: Dr. Donald Menick
Sponsor: MCBP and NIH
October 25, 2007 Steve J. Brill, PhD
Professor
Department of Molecular Biology and Biochemistry
Rutgers University
Piscataway, New Jersey

Title: "Genetic Control of Genome Stability in Yeast: A Novel Ubiquitin Ligase Implicates a Role for Sumoylation"
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
November 1, 2007 NO SEMINAR - Student Research Day (November 2, 2007)  
November 8, 2007 Donald M. Bers, PhD
James R. DePauw Professor of Physiology
Chair, Department of Physiology and NIH Cardiovascular Training
Loyola University Chicago Grant
Stritch School of Medicine
Maywood, Illinois

Title: "Ca and CaMKII in Heart Failure:
Systolic Dysfunction, Arrhythmogenesis & Transcriptional Regulation"
Host: Dr. Don Menick
Sponsor: MCBP Program
November 15, 2007 CANCELLED
Gökhan Hotamisligil, MD, PhD
James Stevens Simmons Professor of
Genetics and Metabolism Biochemistry
Department of Genetics and Complex Diseases
Harvard School of Public Health
Boston, Massachusetts
Host: Dr. Can E. Senkal
Sponsor: Dean’s Seminar Series/
November 22, 2007 Thanksgiving Break  
November 29, 2007 Robert S. Kass, PhD
Chairman, Department of Pharmacology
David Hosack Professor of Pharmacology Cardiovascular Training Grant
Columbia University
New York, New York

Title: "General Lessons from Rare Congenital Arrhythmias"
Host: Dr. Steve Kubalak
Sponsor: MCBP and NIH
December 6, 2007 NO SEMINAR (Room 125 not available)  
December 13, 2007 Susan Forsburg, Ph.D.
Professor
Biological Sciences
University of Southern California
Los Angeles, California

Title: "Replication, Repair, and Chromatin in s. pombe"
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
Spring 2007
January 11, 2007 Mirko Hennig, Ph.D.
Assistant Professor
Department of Biochemistry and Molecular Biology
Medical University of South Carolina

Title: "HIV-1 Latency – The Role of the Regulatory Protein Rev"
 
January 18, 2007 Elizabeth Murphy, Ph.D.
Head, Cardiac Physiology Section
Vascular Medicine Branch
NHLBI, NIH
Bethesda, Maryland

Title: "Cardioprotection: The Role of Mitochondria, Calcium and GSK-3beta"
Host: Dr. Donald R. Menick
Sponsor: MCBP Program
January 25, 2007 No Seminar  
February 1, 2007 P. Darwin Bell, Ph.D.
DCI Professor of Medicine
Medical University of South Carolina

Title: "Macula Densa-Juxtaglomerular Signaling"
 
February 8, 2007 Curtis C. Harris, M.D.
Chief, Laboratory of Human Carcinogenesis
Chief of Molecular Genetics & Carcinogenesis Section
NIH, NCI, CCR
Clinical Professor of Medicine and Oncology
Georgetown University School of Medicine

Title: "Inflammation and Cancer"
Host: Student Peko Tsuji
Dean’s Seminar Series Speaker
February 15, 2007 Daniel M. Raben, Ph.D.
Associate Professor
The Johns Hopkins University

CANCELLED BUT RESCHEDULED FOR APRIL 5, 2007
Host: Dr. Lina Obeid
Sponsor: Biochemistry/MCBP
February 22, 2007 Kyu-Ho Lee, M.D., Ph.D.
Assistant Professor of Pediatrics
Division of Pediatric Cardiology
Cardiovascular Developmental Biology Center
Medical University of South Carolina

Title: "Compartmental Nkx2.5 Regulation Yields Insights Into
Cardiac Induction, Lineage and Fate Decisions"
 
March 1, 2007 Michael V. Johnston, M.D.
Chief Medical Director
Kennedy Krieger Institute
Professor of Neurology, Pediatrics, and
Physical Medicine and Rehabilitation
Johns Hopkins School of Medicine
Baltimore, Maryland

Title: "Clinical Disorders of Brain Plasticity"
Host: Dr. Bernard Maria
Charles P. Darby Children’s Research Institute
March 8, 2007 Jonathan Lytton, Ph.D.
Professor of Biochemistry and
University of Calgary
Canada

Title: "The NCKXs: A Unique Branch of the Sodium-Calcium Exchanger Family"
Host: Dr. Donald Menick
Sponsor: Cardiovascular
Molecular Biology Training Grant and MCBP Program
March 15, 2007 SPRING BREAK – March 10-18, 2007  
March 22, 2007 Jeffrey L. Benovic, Ph.D.
Professor and Chair
Department of Biochemistry and
Molecular Biology
Thomas Jefferson University
Philadelphia, Pennsylvania

Title: "Arresting Developments in Receptor Signaling and Trafficking"
Host: Drs. Perry Halushka and Lou Luttrell
Sponsor: MCBP Program
March 29, 2007 W. Scott Moye-Rowley, Ph.D.
Professor and Executive Associate Head
Department of Molecular Physiology & Biophysics
Carver College of Medicine
University of Iowa
Iowa City, Iowa

Title: "Coordinate Control of Sphingolipid Biosynthesis and Multidrug Resistance"
Host: Dr. Ashley Cowart
Sponsor: Biochemistry
April 5, 2007 Daniel M. Raben, Ph.D.
Associate Professor
Departments of Biological Chemistry,
Oncology and Physiology
The Johns Hopkins University
Baltimore, Maryland

Title: "Dual Regulation of Diacylglycerol Kinase-theta:
An Interfacial Signaling Enzyme"
Host: Dr. Lina Obeid
Sponsor: Biochemistry/MCBP
April 12, 2007 Rachel Wong, Ph.D.
Professor
Department of Biological Structure
University of Washington
Seattle, Washington

Title: "Imaging Circuit Assembly in the Vertebrate Retina"
Host: Dr. Rosalie Crouch
Sponsor: MCBP Program
April 19, 2007 Rosalie C. Sears, Ph.D.
Professor, Department of Genetics
Cancer Institute
Oregon Health & Science University
Portland, Oregon

Title: "A Role for c-Myc Protein Stabilization in Cancer"
Host: Dr. Besim Ogretmen
Sponsor: Biochemistry
April 26, 2007 Alan C. Rapraeger, Ph.D.
Professor and Vice-Chair for Education
Department of Pathology and
Laboratory Medicine
University of Wisconsin
1300 University Avenue
Madison, WI 53706

Title: "Regulation of Integrin Activity by Syndecan-1 during
Tumorigenesis and Angiogenesis"
Host: Dr. Tien Hsu
Sponsor: MCBP Program
Fall 2006

September 21, 2006

Melvin L. DePamphilis, Ph.D., Section Chief
Member, Senior Biomedical Research Service
National Institute of Child Health and Human Development
National Institutes of Health
Bethesda , Maryland

Title: “ORC Cycle: A Novel Mechanism for Regulating Genome Duplication in Mammalian Cells”

Host: Dr. Deepak Bastia
Sponsor: Biochemistry

September 28, 2006

John J. Lemasters, M.D., Ph.D.
South Carolina COEE Endowed Chair in Advanced Cellular Technologies
Pharmaceutical Sciences and Biochemistry and Molecular Biology
Medical University of South Carolina

Title: “Mitochondrial Membrane Permeabilization in Pathogenesis”

 
October 5, 2006 S. Michael Jazwinski (CANCELLED)  

October 12, 2006

Muthu Periasamy, Ph.D.
Professor and Chair
Department of Physiology and Cell Biology
Ohio State University College of Medicine
Columbus , Ohio

Title: “SERCA Pump Rescues Cardiac Function in Ischemic Heart Disease”

Host: Dr. Dhan Kuppuswamy
Sponsor: MCBP Program and NIH Cardiovascular Training Grant

October 19, 2006

Craig D. Logsdon, Ph.D.
Lockton Distinguished Prof. for Pancreatic Cancer Resch
Departments of Cancer Biology and Medical Oncology UT MD Anderson Cancer Center , Unit 953
Houston , TX 77030

Title: “Exploiting Pancreatic Cancer Specific Genes as Therapeutic Targets”

Host: Dr. Michael Mitas
Sponsor: MCBP Program

October 26, 2006

TBA  

November 2, 2006

NO SEMINAR RESEARCH DAY – November 3, 2006

 

November 9, 2006

Jeffrey Rosen, Ph.D.
C.C. Bell Professor of Molecular and Cellular Biology and Medicine
Distinguished Service Professor
Baylor College of Medicine
Houston , Texas

Title: “Stem/progenitor Cells in the Etiology and Treatment of Breast Cancer”

Host: Dr. Dennis Watson
Sponsor: MCBP Program

November 16, 2006

Brian Popko, Ph.D.
Jack Miller Professor in Neurological Diseases
Director, Jack Miller Center for Peripheral Neuropathy
Associate Chair for Research, Department of Neurology University of Chicago
Chicago , Illinois

Title: “ER Stress Modulates the Response of Oligodendrocytes to CNS Inflammation

Host: Dr. Hiroko Hama
Sponsor: Biochemistry

November 23, 2006

THANKSGIVING  

November 30, 2006

Joseph Y. Cheung, M.D., Ph.D.
Capizzi Professor of Medicine
Chief of Nephrology
Thomas Jefferson University
Philadelphia , PA 19107

Title: “Regulation of Cardiac Na/Ca Exchanger by Phospholemman”

Host: Dr. Donald Menick
Sponsor: MCBP Program

December 7, 2006

Ann Ramsdell, Ph.D. Health Science Foundation
Assistant Professor Developing Scholar Lecture Department of Cell Biology and Anatomy
Medical University of South Carolina

Title: “Left-Right Asymmetry and Congenital Cardiac Defects: The Heart of the Matter in Left-Right Axis Determination”

 
Spring 2006

January 12, 2006

 

Joel A. Huberman, Ph.D
Professor Cellular and Molecular Biology
State University of New York at Buffalo
Buffalo, New York

Title: "What is the Difference Between Early-firing and Late-Firing DNA Replication Origins?"

Host: Dr. Deepak Bastia
Sponsor: Biochemistry

 

 

January 19, 2006 Ziad H. Nahas, M.D.
Associate Professor
Department of Psychiatry and Behavioral Sciences
Medical University of South Carolina
Health Sciences Foundation Developing Scholar Award

Title: "Neuromodulation Treatments for Depression"
 
January 26, 2006
Paul B. Fisher, Ph.D.
Professor of Clinical Pathology
Director, Neuro-Oncology Research
Michael and Stella Chernow
Urological Cancer Research Scientist
Columbia University Medical Center
College of Physicians and Surgeons
New York, NY

Title: "Terminal Differentiation and Cellular Senescence: Opposite Sides of the Same Coin"
Host: Dr. Dennis Watson
Sponsor: MCBP
February 2, 2006 Maurizio Del Poeta, M.D.
Associate Professor of Biochemistry & Molecular Biology
Medical University of South Carolina
Health Sciences Foundation Developing Scholar Award

Title: "Sphingolipids in Fungal Pathogenesis: The Role of Glucosylceramide"
 
February 9, 2006 Dr. Fitzgerald (CANCELLED) Host: Dr. Yusuf Hannun
Sponsor: Biochemistry
February 16, 2006 Gary W. Litman, Ph.D.
Professor of Biochemistry & Molecular Biology
University of South Florida
College of Medicine
St. Petersburg, FL

Title: "Reconstructing Immune Phylogeny"
Host: Dr. Greg Warr
Sponsor: MCBP
February 23, 2006 Arnold J. Levine, Ph.D.
Harry C. Wiess Professor in the Life Sciences,
Emeritus Professor of Molecular Biology, Emeritus Professor, Institute for Advanced Study, School of Natural Sciences< Princeton University
Professor, Pediatrics and Biochemistry
Cancer Institute of New Jersey/UMDNJ
New Brunswick, NJ

Title: "A Single Nucleotide Polymorphism in the Human MDM-2 Gene that Modifies the p53 Response and Results in an Early Age of Onset of Cancers"

Host: Dr. Deepak Bastia
Sponsor: Biochemistry

March 2, 2006 Gary Landreth, Ph.D.
Professor
Department of Neurosciences and Neurology
Alzheimer Research Laboratory
Case Western Reserve University School of Medicine
Cleveland, Ohio

Title: "Inflammatory Mechanisms in Alzheimer's Disease"
Host: Don Menick
Sponsor: MCBP
March 9, 2006 George K. Michalopoulos, M.D., Ph.D.
Professor and Chairman
Department of Pathology
University of Pittsburgh School of Medicine
Pittsburgh Pennsylvania

Title: TBA
Host: Dr. Yusuf Hannun
Sponsor: Biochemistry
March 16, 2006 No Seminar - Spring Break  
March 23, 2006 Dianna M. Milewicz, MD, PhD
Professor and Director
Division of Medical Genetics
Department of Internal Medicine
President George H. W. Bush Chair of Cardiac Medicine, Texas Heart Institute
University of Texas Medical School

Title: "Genetic Basis of Aortic Aneurysm and Dissection"
Host: Dr. Perry Halushka
Sponsor: MCBP
March 30, 2006
Phillip A. Sharp, Ph.D.
Institute Professor
Center for Cancer Research
Massachusetts Institute of Technology

Title: "The Surprising Biology of Small RNA"
Host: Mara Lennard, Grad Stud
Sponsor: Biochemistry
April 6, 2006 TBA  
April 13, 2006 David J. Newman, Ph.D.
Natural Products Branch
Developmental Therapeutics Program
National Cancer Institute
Frederick, Maryland
Host: Dr. Peter Moeller & Tracey Schock
Sponsor: MCBP
April 20, 2006 H. Alex Brown, Ph.D.
Ingram Associate Professor of Cancer Research
Vanderbilt University

Title: TBA
Host: Dr. Lina Obeid
Sponsor: Biochemistry
April 27, 2006 Henk E.D.J. ter Keurs
Professor
Department of Physiology and Biophysics
University of Calgary
Calgary, Alberta, Canada

Title: "Non Uniform Contraction of Myocardium is Arrhythmogenic: A Role of Calcium Dissociation from the Myofilaments"
Host: Dr. George Cooper
Sponsor: MCBP
Fall 2005
Sept. 29, 2005
Silvia Finnemann, Ph.D.
Associate Professor of Cell Biolog in Ophthalmology
Dyson Vision Research Institute
Weill Medical College of Cornell University
New York, New York

Title:  "Timing is Everything: Control of Daily Retinal Phagocytosis and Adhesion by Integrin Receptor Signaling"
Host:  Dr. Rosalie Crouch
Sponsor:  MCBP Program
 
October 6, 2005
Thomas H. Fischer, Ph.D.
Research Associate Professor
Department of Pathology and Laboratory Medicine
University North Carolina
Chapel Hill, North Carolina

Title:  "Bioengineering of Rehydrated, Lyophilized Platelets for Vascular Wound Site Imaging and Stabilization" 
Host:  Dr. Robin Muise-Helmericks
Sponsor:  MCBP Program
October 13, 2005
Masayori Inouye, Ph.D.
Professor and Chairman
Department of Biochemistry
University of Medicine and Dentistry of New Jersey
Robert Wood Johnson Medical School
Piscataway New Jersey

Title:  "mRNA Interferase, a Novel Mechanism for Cell Growth Regulation"
Host:  Dr. Hiroko Hama
Sponsor:  Biochemistry
October 20, 2005
Kenneth D. Poss, Ph.D.
Assistant Professor
Cardiovascular Training Grant
Duke University
Durham, North Carolina

Title:  "Molecular Insights into Heart Regeneration in Zebrafish"
Host:  Dr. Steve Kubalak
Sponsor:  MCBP Program and Department of Cell Biology
October 27, 2005
Donald M. Bers, Ph.D.
Professor and Chair of Physiology
Loyola University Stritch
School of Medicine
Mayfield, Illinois

Title:  "Ca and CaMKII in Cardiac EC-Coupling and Nuclear Signaling in Heart Failure"
Host:  Dr. Donald Menick
Sponsor:  MCBP Program and Cardiovascular Training Grant
November 3, 2005 (No seminar — Research Day November 4, 2005)  
November 10, 2005
Xiaojiang Chen, Ph.D.                            
Professor of Biological Chemistry
University of Southern California
Los Angeles, California

Title:  "Two Headed Helicases:  Unwinding Double Helix DNA"
Host:  Dr. Deepak Bastia
Sponsor:  Biochemistry
November 17, 2005
Jeffrey E. Green, M.D.
Senior Investigator and Head
Transgenic Oncogenesis Group
Laboratory of Cell Regulation and Carcinogenesis
National Cancer Institute
Bethesda, Maryland

Title:  "Conservation of Dysregulated Genetic Networks in Mouse and Human Mammary Cancer:  Sifting Through the Haystack Using Systems Biology"
Host:  Dr. Dennis Watson
Sponsor:  MCBP Program
November 24, 2005 November 24, 2005     (No seminar — Thanksgiving)
 
December 1, 2005
D. Woodrow Benson, M.D., Ph.D.
Professor of Pediatrics
Director, Cardiovascular Genetics
Cincinnati Children's Hospital
Medical Center
Cincinnati, Ohio

Title:  "Genetic and Developmental Origins of Pediatric Heart Valve Disease"
Host:  Dr. Terry O'Brien
Sponsor:  MCBP Program and Cardiovascular Training Grant
December 8, 2005
Michael A. Frohman, M.D., Ph.D.          
Professor of Pharmacology                   
Director, Medical Scientist Training Programz
SUNY at Stony Brook, New York

Title:  "Mito-PLD, a Novel Lipid-Modifying Enzyme That Regulates Mitochondrial Fusion"
Host:  Dr. Yusuf Hannun
Sponsor:  Biochemistry
Spring 2005   
January 27, 2005 Stanley H. Appel, M.D.
Professor, Department of Neurology
Baylor College of Medicine
Houston, TX

Title: "Inflammation: The Good, the Bad, and The Ugly: Lessons from ALS"
Host: Dr. William R. Tyor
Sponsor: MCBP
February 3, 2005 Ronald H. Kaback, M.D.
HHMI Investigator and Professor
UCLA
Los Angeles, CA

Title: The Passion of the Permease: from Membrane to Molecule to a Mechanism of Active Transport"
Host: Dr. Donald Menick
Sponsor: MCBP
February 10, 2005 John A. McDonald, M.D., Ph.D.
Dean, School of Medicine and Vice President for Health Sciences, Reno School of Medicine
University of Nevada
Reno, Nevada

Title" "A Link Between Integrins, Calreticulin and Systolic Dysfunction Revealed by Conditional Transgene Expression in the Adult Mouse Heart"
Host: Dr. George Cooper
Sponsor: MCBP
March 3, 2005 Kenneth R. Chien, M.D., Ph.D.
Director, Institute of Molecular Medicine
UCSD School of MedicineSan Diego, California

Title:  “Islet-1 Cardiac Progenitors in Development and Disease” 
Host:  Dr. Steve Kubalak & Sponsor: MCBP
March 10, 2005 Kenneth D. Tew, Ph.D., DSci       
Professor and Chair, Department of Cell and Molecular Pharmacology and Experimental Therapeutics
Medical University of South Carolina

Title:  “Islet-1 Cardiac Progenitors in Development and Disease” 
 
March 24, 2005 Besim Ogretmen, Ph.D.                        
Assistant Professor of Biochemistry and Molecular Biology
Medical University of South Carolina
                        
Title: “ The Role Ceramide in the Regulation of Cancer Growth and Therapy”
 
March 31, 2005 Fuad Ziyadeh, M.D.                                          
Professor of Medicine                                         
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania

Title:  "Pathogenesis of Diabetic Nephropathy: Role of TGF-beta and VEGF"
Host:  Dr. Ayad Jaffa
Sponsor:  MCBP
April 7, 2005 Rodney Rothstein, Ph.D.                                     
Professor
Genetics and Development                                  Columbia University
College of Physicians and Surgeons
New York, New York


Title:  “Choreography of the DNA Damage Response in Budding Yeast”
Host: Dr. Deepak Bastia
Sponsor:  Biochemsitry
April 14, 2005 Thomas A. Steitz, Ph.D.                            
Sterling Professor and HHMI Investigator                        Yale University
Branford, Connecticut

Title: "Motion in Macromolecular Machines"
Host:  Dr. Jeff Hansen
Sponsor:  Biochemistry
April 21, 2005 David J. Ecker, Ph.D.President
Division of Isis Therapeutics
Isis Pharmaceutics
Carlsbad, California

Title:  "Technology for Universal Infectious Disease Identification"
Host:  Dr. Donald Menick
Sponsor:  MCBP
April 28, 2005 David J. Kusner, M.D., Ph.D.
Associate Professor
Departments of Internal Medicine,
Immunology, Molecular Biology, & Physiology/Biophysics
University of Iowa
Inflammation Program
Coralville, Iowa

Title:  The role of sphingosine kinase in macrophage function and disease pathogenesis”
Host:  Dr. Lina Obeid
Sponsor:  MCBP
May 5, 2005 Jerry W. Shay, Ph.D.
Professor of Cell Biology
Southland Financial Distinguished
Chair in Geriatric Research
Associate Director, Cancer Center
University of Texas Southwest
Dallas, Texas

Title: "Aging and Cancer: Are Telomeres and Telomerase the Connection?"
Host:  Dr. Besim Ogretmen
Sponsor:  Biochemistry
Fall 2004
Sept. 16, 2004 Robert K. Yu, Ph.D, MedScD
Director and Professor
Institute of Molecular Medicine and Genetics
Medical College of Georgia School of Medicine
Augusta GA

Title: "Developmental Regularion of Ganglioside Metabolism in the Nervous System"
Host: Dr. Yusuf Hannun
Sponsor: Biochemistry
Sept. 23, 2004 Joseph Heitman, MD, PhD
Associate Investigator HHMI
Professor
Duke University Medical Center
Durham, North Carolina

Title: "Evolution of the Model Human Fungal Pathogen Cryptococcus Neoformans"
Host: Dr. Maurizio Del Poeta
Sponsor: Biochemistry
Sept. 30, 2004 Bryan P. Toole, PhD
Professor of Cell Biology and Anatomy
Medical University of South Carolina

Title: "Hyaluronan and Emmprin: Pericellular Regulators of ErbB2 Signaling, Multidrug Resistance and Malignant Cell Behavior"
 
Oct. 7, 2004 Morris F. White, Ph.D.
Associate Professor of Pediatrics
Department of Chemistry and Molecular Pharmacology
Howard Hughes Medical Institute
Harvard Medical School
Boston, Massachusetts

Title: "The Role of Irs2 Signaling in Obesity and Diabetes"
Host: Dr. Maria Buse
Sponsor: MCBP Program
Oct. 14, 2004 J. Marie Hardwick, PhD
Professor
Department of Molecular Microbiology and Immunology
Johns Hopkins Bloomberg School of Public Health

Title: TBA
Host: Yi-Te Hsu
Sponsor: Biochemistry
Oct. 21, 2004 John W. Baynes, PhD
Carolina Distinguished Professor
Department of Chemistry and Biochemistry
University of South Carolina
Columbia, South Carolina

Title: "Chemical Modification of Proteins in Aging, Diabetes and Cardiovascular Disease: The Relationship Between Metabolism and Chemistry in Disease"
Host: Dr. Hiroko Hama
Sponsor: Biochemistry
Oct. 28, 2004 Richard P. Visconti, PhD
Assistant Professor of Cell Biology and Anatomy
Medical University of South Carolina

Title: "Adult Bone Marrow Stem Cells in Cardiac Homeostatis and Pathology"
 
Nov. 4, 2004 Rowena G. Matthews, PhD
G. Robert Grennberg Professor and Senior Research Scientist, Life Sciences Institute
University of Michigan
Ann Arbor, Michigan

Title: "Regulation of One-carbon Metabolism in Mammals"
Host: Dr. Sergey Krupenko
Sponsor: Biochemistry
Nov. 11, 2004 Robert A. Nicholas, PhD
Professor, Department of Pharmacology
University of North Carolina
Chapel Hill, North Carolina

Title: "Antibiotic Resistance in Neisseria gonorrhoeae: Cumulative Effect of Multiple Resistance Genes"
Host: Dr. Chris Davies
Sponsor: Biochemistry
Nov. 18, 2004 Emily Wilson, PhD
Assistant Professor
Department of Medical Physiology
Texas A&M Health Science Center
College Station, Texas

Title: "Modulation of Integrin Expression and Function During Vascular Remodeling:
Host: Dr. Don Menick
Sponsor: MCBP Program
Nov. 25, 2004 Thanksgiving  
Dec. 2, 2004 John P. Sundberg, DVM, PhD
Senior Staff Scientist
The Jackson Laboratory
Bar Harbor, Maine

Title: "Mouse Models for Dermatological Research"
Host: Dr. Alexander Awgulewitsch
Sponsor: MCBP Program
Spring 2004
February 5, 2004 Eleanor K. Spicer, Ph.D.
Associate Professor
Department of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Post-transcriptional Regulation of the bcl-2 Oncogene

February 12, 2004 Craig C. Beeson, Ph.D.
Associate Professor Department of Pharmaceutical Sciences
Medical University of South Carolina
Charleston, South Carolina

Title: Mechanisms for the Coupling of Respiration and Glycolysis
 
February 19, 2004 Ron Peterson, Ph.D.
Fellow, Laboratory Head
Integrated Expression Profiling
Novartis Institute of Biomedical Research

Title: Pharmacogenomic Analysis of rhIL-11 Effects
Host: Dr. Alexander Awgulewitsch
Sponsor: MCBP Program
February 26, 2004 Jason D. Morrow, M.D.
Profesor of Medicine and Pharmacology
Chair, Department of Pharmacology
Vanderbilt University School of Medicine
Nashville, Tennessee

Title: The Isoprostanes - Their Role as Mediators and Markers of Lipid Peroxidation: New Insights and Current Controversies
Host: Dr. Lina Obeid
Sponsor: MCBP Program
March 4, 2004 Michael F. Summers, Ph.D.
Professor
Department of Chemistry and Biochemistry
Howard Hughes Medical Institute Scholar
University of Maryland Baltimore County
Baltimore, Maryland

Title: NMR Studies of Retroviral Genome Recognition and Assembly
Host: Dr. Perry Halushka
Sponsor: MCBP Program
March 11, 2004 Jerry Hurwitz, Ph.D.
Vice Chairman, Sloan-Kettering Institute
Memorial Sloan-Kettering Cancer Center
New York, New York

Title: Studies on Eukaryotic DNA Replication
Host: Dr. Deepak Bastia
Sponsor: Biochemistry
March 18, 2004 Richard J. Youle, Ph.D.
Section Chief of Biochemistry
Surgical Neurology Branch
NINDS, NIH
Bethesda, Maryland

Title: Role of Bcl-2 Family Proteins and Mitochondria Morphology in Apoptosis
Host: Dr. Yi-Te Hsu
Sponsor: Biochemistry
March 25, 2004 Ian A. Blair, Ph.D.
A.N. Richards Professor of Pharmacology
Professor of Chemistry
Director, Center for Cancer Pharmacology
Scientific Director, Genomics Institute Proteomics Facility University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania

Title: Cyclooxygenase-Mediated DNA Damage
Host: Dr. Perry Halushka
Sponsor: MCBP Program
April 1, 2004 Kenneth D. Philipson, Ph.D.
Professor
Department of Physiology and Medicine
Cardiovascular Research Lab
UCLA
Los Angeles, California

Title: Cardiac Sodium-Calcium Exchange: From Molecule to Mouse
Host: Dr. Don Menick
Sponsor: MCBP Program
April 8, 2004 Michael Zasloff, Ph.D.
Dean, Research and Translational Science
Georgetown University Medical Center
Washington, D.C.

Title: Antimicrobial Peptides of Animals in Health and Diseases
Host: Dr. Paul Gross
Sponsor: Biochemistry
April 15, 2004 NO SEMINAR
 
April 22, 2004 Christian R. Raetz, M.D., Ph.D.
Professor and Chairman
Department of Biochemistry
Duke University Medical Center
Durham, North Carolina

Title: Assembly, Secretion and Function of Gram-negative Endotoxin: A Potent Lipid Activator of Innate Immunity
Host: Dr. Yusuf Hannun
Sponsor: MCBP Program
April 29, 2004 NO SEMINAR
 
May 6, 2004 Alfonso Bellacosa, M.D.
Human Genetics Program
Population Science Division
Fox Chase Cancer Center
Philadelphia, Pennsylvania

Title: Role of the MED1 (MBD4) Gene in DNA Repair and Human Cancer or DNA Repair and Cancer Susceptibility
Host: Dr. Robin Muise-Helmericks
Sponsor: MCBP Program
Fall 2003
September 25, 2003 Paul A Marks, M.D.
Professor of Medicine
Memorial Sloan Kettering Cancer Center
New York, New York

Title: Histone Deacetylase Inhibitors
Host: Dr. Gary Gilkeson
Sponsor: MCBP Program
October 2, 2003 Christopher Davies, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina
Developmental Scholar Award

Title: Glycolysis Under Extreme Conditions: A Novel Enzyme in Pyrococcus Furiosus
 
October 9, 2003 Amar J.S. Klar, Ph.D.
Developmental Genetics Section
Gene Regulation and Chromosome Biology Laboratory
NCI Center fro Cancer Research
Frederick, Maryland

Title: Two Independent Epigenetic Events Regulate Fission Yeast Mating-type Switching and Silencing
Host: Dr. Deepak Bastia
Sponsor: MCBP Program
October 16, 2003 Robert S. Kass, Ph.D.
David Hosack Professor of Pharmacology
Chair, Department of Pharmacology
Center for Neurobiology and Behavior
Columbia University
New York, New York

Title: Clinical and Basic Studies of Inherited Cardiac Arrhythmias: Novel Insight into the Molecular Physiology Pharmacology of Ion Channels in the Heart
Host: Dr. Steve Kubalak
Sponsor: MCBP Program
October 23, 2003 Swapan K. Ray, Ph.D.
Assistant Professor
Department of Neurology
Medical University of South Carolina
Charleston, South Carolina

Title: Experimental Therapeutics for Activation of Apoptosis in Glioblastoma
 
October 30, 2003 Meenakshi A. Chellaiah, Ph.D.
Assistant Professor
Oral Cranio Biological Sciences
University of Maryland
Baltimore, Maryland

Title: Molecular Basis of Cytoskeletal Reorganization in Osteoclasts in Response to Integrin avb3 Activation
Host: Dr. Dhan Kuppuswamy
Sponsor: MCBP Program
November 6, 2003 TBA

November 13, 2003 M. Rita Young, Ph.D.
Professor of Medicine
Division of Hematology/Oncology
Medical University of South Carolina
AOCS, Ralph H. Johnson VA Medical Center Charleston, South Carolina

Title: The Role of CD34+ Progenitor Cells in Tumor Progression
 
November 20, 2003 Howard A. Rockman, M.D.
Professor of Medicine
Department of Cell Biology and Genetics
Duke University Medical Center
Durham, North Carolina

Title: Novel Insights into Heptahelical Receptor Signaling in the Heart
Host: Dr. Steve Kubalak
Sponsor: Cardiovascular Training Grant
November 27, 2003 Thanksgiving
 
December 4, 2003 TBA
 
December 11, 2003 Hamid Band, M.D., Ph.D.
Professor of Medicine
Feinberg School of Medicine
Northwestern University
Director, Division of Molecular Oncology
Evanston Northwestern Healthcare Research Institute
Evanston, Illinois

Title: Negative Regulation of Tyrosine Kinases by Cb1 Family of Ubiquitin Ligases
Host: Dr. Dennis Watson
Sponsor: MCBP Program
Spring 2003
January 16, 2003 Jay A. Tischfield
Duncan and Nancy MacMillan Professor of Genetics
Chair Department of Genetics
Nelson Biological Labs
Rutgers University
Piscataway, New Jersey

Title: Mechanisms of Loss of Heterozygosity in Somatic Cells of Mice and Humans
Host: Dr. Donald R. Menick
Sponsor: MCBP Program
January 23, 2003 Cancelled

January 30, 2003 Barry T. Hinton, Ph.D.
Professor of Cell Biology
University of Virginia School of Medicine
Charlottesville, Virginia

Title: Testicular Luminal Growth Factors as Regulators of Epididymal Gene Expression
Host: Dr. Demetri Spyropoulos
Sponsor: MCBP Program
February 6, 2003 Kuo-Chen Chou, D.Sc., Ph.D.
Senior Research Advisor
Computer-Aided Drug Discovery
Research and Development
Pharmacia Corporation

Title: Protein Attribute Prediction - A New Branch in Proteomics
Host: Dr. Perry V. Halushka
Sponsor: MCBP Program
February 13, 2003 Mark S. Kindy, Ph.D.
Admiral Pihl Chair and Professor
Department of Physiology and Neuroscience
Director of the Stroke Program of MUSC
Associate Director, Center on Aging
Assoc. Director of the South Carolina Spinal Cord Center
Medical University of South Carolina

Title: Stroke: Molecular Mechanisms of Disease
 
February 20, 2003 Developing Scholars Seminar
Sergey A. Krupenko, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: 10-Formyltetrahydrofolate Dehydrogenase: Structure, Function and its Role in Cellular Proliferation

February 27, 2003 Peter W. Kalivas, Ph.D.
Professor and Chair
Department of Physiology and Neuroscience
Medical University of South Carolina
Charleston, South Carolina

Title: Addiction: A Pathology in Molecular Mechanisms of Memory
 
 
March 6, 2003 Amy Bradshaw, Ph.D.
Assistant Professor of Medicine (Cardiology)
Medical University of South Carolina
Charleston, South Carolina

Title: Cell Design of the Extracellular Matrix: Alterations in Collagen Structure and Composition Influence Cell Behavior

March 13, 2003 Spring Break

March 20, 2003 William L. Smith, Ph.D.
Professor of Biochemistry
Michigan State University
East Lansing Michigan

Title: Fatty Acid Cyclooxygenase: Structure and Function
Host: Dr. Perry V. Halushka
Sponsor: MCBP Program
March 27, 2003 TBA
April 3, 2003 Merry Lindsey, Ph.D.
Assistant Professor
Department of Surgery
Medical University of South Carolina
Charleston, South Carolina

Title: Identifying MMP-9 Roles Following MI: Elucidating Mechanisms of MMP Function in the Remodeling Myocardium
Host: Dr. Frank Spinale
Sponsor: Division of Cardiothoracic Surgery
April 10, 2003 Sherman Weissman, Ph.D.
Sterling Professor of Human Genetics
Director of Molecular Oncology and Development
Boyer Center for Molecular Medicine
Yale University New Haven, Connecticut

Title: Mammalian Molecular Biology on a Genomic Scale. Three Billion Bases Are Easy and 700 Are Hard
Host: Dr. Depak Bastia
April 17, 2003 Gary Nabel, M.D., Ph.D.
Director, VRC
National Institutes of Health
Bethesda, Maryland

Title: How Do Viruses Kill Cells?
Host: Dr. Jim Norris
Sponsor: MCBP Program
April 24, 2003 TBA

May 1, 2003 Armen Manoukian, Ph.D.
Associate Professor
Department of Medical Biophysics
Ontario Cancer Institute
University of Toronto
Toronto, Canada

TBA
Host: Dr. Tien Hsu
Sponsor: MCBP Program
May 8, 2003

William Dowhan, Ph.D.
Professor and John S. Dunn Chair
Department of Biochemistry and Molecular Biology, and Microbiology
University of Texas-Houston Medical Center
Houston, Texas

Title: Role of Cardiolipin and Phosphatidylglycerol in Mitochondrial Function
Host: Dr. Yusuf Hannun
Sponsor: Biochemistry and Molecular Biology
May 22, 2003 Richard L Proia, Ph.D.
Chief, Genetics of Development and Disease Branch
NIDDK, National Institutes of Health
Bethesda, Maryland

Title: Role of Sphingolipids in Signaling by Tyrosine Kinase and G-protein Coupled Receptors
Host: Dr. Yusuf Hannun
Sponsor: Biochemistry and Molecular Biology
Fall 2002
September 26, 2002 Daria Mochly-Rosen, Ph.D.
Professor and Chief
Department of Molecular Pharmacology
Stanford University School of Medicine
Stanford, California

Title: PKC and Cardiac Function: A Tale of Protein-Protein Interactions
Host: Dr. Frank Spinale
Sponsor: Cardiothoracic Surgery
October 3, 2002 H. Leighton Grimes, Ph.D.
Assistant Professor
Institute of Cell Therapeutics
University of Louisville
Louisville, Kentucky

Title GFI1 Oncoprotein: Cell Fate Determination in Lymphopoiesis and Epithelial Malignancy
Host: Robin Muise-Helmericks, PhD
Sponsor: MCBP Program
October 17, 2002 Robert G. Gourdie, Ph.D.
Associate Professor
Department of Cell Biology and Anatomy
Medical University of South Carolina
Charleston, South Carolina

Title: Conducting the Heart Beat: Orchestrating Development of Specialized Pathways for Propagation of Cardiac Action Potential
 
October 24, 2002 Donald M. Bers, Ph.D.
Professor and Chair
Department of Physiology
Loyola University, Stritch School of Medicine
Chicago, Illinois

Title: Sodium and Calcium in Cardiac Myocytes: Involvement in Contractile Function and Arrhythmogenesis in Heart Failure
Host: Dr. Donald Menick
Sponsor: MCBP Program
October 31, 2002 David L. Williams, Ph.D.
Professor of Surgery
James H. Quillen College of Medicine
East Tennessee State University
Johnson City, Tennessee

Title: Potential Role of the Phosphoinositide 3-Kinase Signaling Pathway in the Response to Polymicrobial Sepsis and Septic Shock
Host: Dr. James A. Cook
Sponsor: MCBP Program
November 7, 2002 CANCELLED TO BE RESCHEDULED Dr. Frank Spinale
Dr. Rupak D. Mukherjee
Cardiothoracic Surgery
November 14, 2002 John D. Hildebrandt, Ph.D.
Professor and Chair
Department of Cell and Molecular Pharmacology
Medical University of South Carolina
Charleston, South Carolina

Title: Generation and Function of G Protein Subunit Diversity

Host: Dr. Shailesh Patel
Sponsor: Department of Medicine and MCBP Program

November 21, 2002

Lei Yu, Ph.D.
Professor
Department of Cell Biology, Neurobiology, and Anatomy
University of Cincinnati College of Medicine
Cincinnati, Ohio


Title: The Opioid System and Its Role in Physiological Modulation

Host: Dr. Donald Menick
Sponsor: MCBP Program
November 28, 2002 Thanksgiving - NO SEMINAR  
December 5, 2002

William M. Chilian, Ph.D.



TBA
Host: Dr. George Cooper
Sponsor: Cardiology Division/Department of Medicine
MCBP Program
December 12, 2002 David R. Clemmons, M.D.
Professor of Medicine
Sarah Graham Kenan
Professor of Medicine
Chief, Division of Endocrinology and Metabolism
University of North Carolina
Chapel Hill, North Carolina

Title: Cooperative Interactions Among Three Integral Membrane Proteins in Controlling IGF-1 Receptor Activation
Host: Dr. Steven A Rosenzweig
Sponsor: MCBP Program
Spring 2002
January 10, 2002 Robert W. Thompson, M.D.
Professor of Surgery and Cell Biology
Washington University School of Medicine
St. Louis, Missouri

Title: Matrix Metalloproteinases and Vascular Remodeling
Host: Dr. Frank Spinale
Sponsor: Cardiothoracic Surgery
January 17, 2002 Hiroko Hama, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Phosphoinositide Regulation of Membrane Trafficking in Saccharomyces Cerevisiae
 
January 24, 2002 CANCELLED  
January 31, 2002 Fernando R. Cabral, Ph.D.
Associate Professor
Department of Integrative Biology and Pharmacology
University of Texas Medical School
Houston, Texas

Title: The Role of Microtubule Assembly in Resistance to Cancer Drugs
Host: Dr. George Cooper
Sponsor: Cardiothoracic Surgery
February 7, 2002 Deepak Bastia, Ph.D.
Professor
Department of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Mechanism of Initiation and Termination of DNA Replication in Bacteria and Yeast
 
February 14, 2002 Steven A Rosenzweig, Ph.D.
Professor
Department of Cell and Molecular Pharmacology
Medical University of South Carolina
Charleston, South Carolina

Title: Targeting the Insulin-like Growth Factor System for the Development of Novel Therapeutics
 
February 21, 2002 Joyce J. Repa, Ph.D.
Assistant Professor
Departments of Physiology and Internal Medicine
Touchstone Center for Diabetes Research
University of Texas Southwestern Medical Center
Dallas, Texas

Title: Nuclear Orphan Receptor Regulation of Cholesterol and Bile Acid Metabolism
Host: Dr. Shailesh Patel
Sponsor: Department of Medicine and MCBP Program
February 28, 2002 John M. Arthur, M.D., Ph.D.
Associate Professor of Medicine (Nephrology)
Medical University of South Carolina
Charleston, South Carolina

Title: Proteomics: Principles and Applications
 
March 7, 2002 Frank J. Rauscher, III, Ph.D.
Professor and Chairman
The Molecular Genetics Program
Deputy Director
The Wistar Institute Cancer Center
Philadelphia, Pennsylvania

Title: Functions of the KRAB Domain Superfamily of Zinc-Finger Repressors: A Paradigm for Coordinating Histone De-acetylation, Methylation and Heterochromatin Formation?
Host: Dr. Dennis Watson
Sponsor: MCBP Program
March 14, 2002 Basilia Zingarelli, M.D., Ph.D.
Assistant Professor
Division of Critical Care Medicine
University of Cincinnati Children's Hospital
Cincinnati, Ohio

Title: Nuclear Control of Inflammation: A Role of Poly (ADP-ribosyl)ation
Host: Jim Cook
Sponsor: Department of Physiology and MCBP Program
March 21, 2002 Gerardo R. Vasta, Ph.D.
Professor
Center of Marine Biotechnology
University of Maryland Biotechnology Institute

Title: Innate Immunity in Invertebrates: Self/Non-Self Recognition by the Host, and Parasite Adaptations for Entry and Survival
 
March 28, 2002 Jon Y. Takemoto, Ph.D.
Professor of Biology
Utah State University
Logan, Utah

Title: Novel Antifungal Action by Pseudomonad Cyclic Lipodepsipeptides
Host: Dr. Hiroko Hama
Sponsor: MCBP Program and Department of Biochemistry
April 4, 2002 Gregory W. Warr, Ph.D.
Professor
Department of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Transcriptional Enhancers and the Evolution of Immunoglobulin Genes
 
April 11, 2002 CANCELLED  
April 18, 2002 David C. Gadsby
Director
Lab Cardiac and Membrane Physiology
Rockefeller University
New York, New York

Title: Control of CFTR channel opening and closing by ATP binding and hydrolysis
Host: Dr. Don Menick
Sponsor: MCBP Program
April 25, 2002 No Seminar  
May 2, 2002 M. Elizabeth Fini
New England Eye Center
Tufts University
Boston, Massachusetts

Title: New Roles for Matrix Metalloproteinase Gelatinase B.
Host: Dr. Frank Spinale
Sponsor: Cardiothoracic Surgery
Fall 2001
September 13, 2001 Robert W. Thompson, M.D.
Professor of Surgery and Cell Biology
Washington University School of Medicine
St. Louis, Missouri

Title: New Insights into Vascular Aneurysmal Disease: Translating Basic Discoveries into Therapeutic Modalities
Host: Frank Spinale, M.D., Ph.D.
Sponsor: Cardiothoracic Surgery
September 20, 2001 Besim Ogretmen, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Molecular Mechanisms of the Regulation of Telomerase by Ceramide in Human Lung Cancer Cells
 
September 27, 2001 Rick G. Schnellman, Ph.D.
Professor and Chair
Department of Pharmaceutical Sciences
Medical University of South Carolina
Charleston, South Carolina

Title: Calcium and Calpains in the Inititation and Progression of Cell Death
 
October 4, 2001 Jeffrey Molkentin, Ph.D.
Assistant Professor
Children's Hospital Medical Center
Cincinnati, Ohio

Title: Signal Transduction Pathways Controlling Heart Maturation and Hypertrophy
Host: Frank Spinale, M.D., Ph.D.
Sponsor: Cardiothoracic Surgery
October 11, 2001 Cancelled
 
October 18, 2001 Salih J. Wakil, Ph.D.
Professor and Chairman
Department of Biochemistry and Molecular Biology
Baylor College of Medicine
Houston, Texas

Title: The Role of Acetyl-CoA Carboxylase 2 in Fatty Acid Metabolism and Energy Homeostasis
Host: Yusuf Hannun, M.D.
Sponsor: Department of Biochemistry and Molecular Biology
October 25, 2001 Michael B. O'Connor, Ph.D.
Associate Investigator
Department of Genetics, Cell Biology and Development
HHMI, University of Minnesota
Minneapolis, Minnesota

Title: BMP Signaling Regulates Synapse Development and Function at the Neuromuscular Junction in Drosophila
Host: Tien Hsu, Ph.D.
Sponsor: MCBP Program
November 1, 2001 Frank J. Rauscher, III, Ph.D.
Professor and Chairman
The Molecular Genetics Program
Deputy Director
The Wistar Institute Cancer Center
Philadelphia, Pennsylvania

Title: Functions of the KRAB-domain Superfamily of Zinc-Finger Repressors: A Paradigm for Coordinating Histone De-acetylation, Methylation and Heterochromatin Formation
Host: Dennis Watson, Ph.D.
Sponsor: MCBP Program
November 8, 2001 Timothy Hla, Ph.D.
Professor of Physiology, and Genetics and Developmental Biology
Director, Center for Vascular Biology
University of Connecticut School of Medicine
Farmington, Connecticut

Title: Sphingosine 1-phosphate as an Angiogenic Modulator
Host: Lina Obeid, M.D.
November 15, 2001 Myles C. Cabot, Ph.D.
Chief, Breast Cancer Research Program
John Wayne Cancer Institute
Santa Monica, California

Title: Targeting Ceramide Metabolism as an Approach to Cancer Treatment
Host: Yusuf Hannun, M.D.
November 22, 2001 Thanksgiving
 
November 29, 2001 Simon Conway, Ph.D.
Associate Professor
Institute of Molecular Medicine and Genetics
Medical College of Georgia
Augusta, Georgia

Title: Molecular Analysis of Embryonic Heart Development
Host: Donald R. Menick, Ph.D.
Sponsor: MCBP Program
December 6, 2001 Arturo Casadevall, M.D, Ph.D.
Professor, Department of Microbiology And Immunology
Albert Einstein College of Medicine
Yashiva University
Bronx, New York

Title: Cryptococcus Neoformans: A Pathogen in Black and White
Host: Maurizio Del Poeta, M.D.
Sponsor: Department of Biochemistry and Molecular Biology
Spring 2001
Jan. 18, 2001 Leslie Leinwand, Ph.D.
Professor of Molecular and Cell Developmental Biology
University of Colorado
Boulder, Colorado

Title: Molecular Mechanisms of Hypertrophy and Failure
Host: Dr. George Cooper
Sponsor: MCBP Program
The Adult Cardiology Division
Jan. 25, 2001 Masashi Yanagisawa, M.D., Ph.D.
Investigator & Professor
Department of Molecular Genetics
Howard Hughes Medical Institute
University of Texas Southwestern Medical Institute
Dallas, Texas

TBA
Host: Dr. Shailesh Patel
Feb. 1, 2001 James T. McLaughlin, Ph.D.
Assistant Professor of Physiology and Neuroscience
Medical University of South Carolina
Charleston, South Carolina

Title: Exploring Specificity of Calcium Channel Signaling in Neuroendocrine Cells
 
Feb. 8, 2001 L. Courtney Smith, Ph.D.
Assistant Professor of Biology and Genetics
Department of Biological Sciences
Institute of Biomedical Sciences, Programs in Genetics & Immunology
George Washington University
Washington, D.C.

Title: The Ancestral Innate Immune System in Sea Urchins
Hosts: Matthew Jenny
Dr. Greg War
Feb. 15, 2001 Linda C. McPhail, Ph.D.
Professor, Department of Biochemistry
Wake Forest University School of Medicine
Winston-Salem, North Carolina

TBA

Host: D. Yusuf Hannun
Sponsor:
MCBP Program
Dept. of Biochemistry and Molecular Biology

Feb. 22, 2001 James E. Hall, Ph.D.
Professor, Department of Physiology & Biophysics
University of California - Irvine
Irvine, California

TBA
Host: Dr. Kevin Schey
March 1, 2001 John H. Exton, M.D., Ph.D.
Professor, Departments of Molecular Physiology, Biophysics, and Pharmacology
Howard Hughes Medical Institute
Vanderbilt University
Nashville, Tennessee

Title: Structure, Function, and Regulation of MAP Kinase Pathways
Host: Dr. Yusuf Hannun
Sponsor: MCBP Program
Dept. of Biochemistry and Molecular Biology
March 8, 2001 Melanie H. Cobb, Ph.D.
Professor, Department of Pharmacology
University of Texas Southwestern Medical Center
Dallas, Texas

Title: Structure, Function, and Regulation of MAP Kinase Pathways
Dr. Donald R. Menick
March 15, 2001 SPRING BREAK
 
March 22, 2001 Robin Muise-Helmericks, Ph.D.
Assistant Professor of Cell Biology and Anatomy
Hollings Cancer Institute
Medical University of South Carolina
Charleston, South Carolina

Title: Functional Role of Akt and Ets 1 in Angiogenesis
 
March 29, 2001 Roger H. Reeves, Ph.D.
Professor, Department of Physiology
The Johns Hopkins University School of Medicine
Baltimore, Maryland

Title: Tales from the MICU (Mouse Intensive Care Unit): QTL Mapping and the inflammatory Response
Host: Dr. Dennis Watson
April 5, 2001 Marsha Rosner, Ph.D.
Director, and Charles B. Huggins Professor
Ben May Institute for Cancer Research
University of Chicago
Chicago, Illinois

Title: Specificity in MAP Kinase Signaling Pathways
Host: Dr. Steve Rosensweig
April 12, 2001 Thoru Pederson, Ph.D.
President and Director
Worcester Foundation for Biomedical Research
Shrewsbury, Massachusetts

TBA
Host: Dr. Paul McDermott
Sponsor: MCBP Program
The Adult Cardiology Division
April 19, 2001 David K. Perry, Ph.D.
Instructor of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Regulation of De Novo Ceramide in Cellular Stress
 
Fall 2000
Sep. 14, 2000 James Cook, Ph.D.
Professor of Physiology and Neuroscience
Medical University of South Carolina
Charleston, South Carolina

Title: Endotoxin Signal Transduction Pathways and Their Alterations in Endotoxin Tolerance
 
Sep. 21, 2000 Joseph S. Janicke, Ph.D.
Professor, Department of Anatomy, Physiology & Pharmacology
Auburn University
Auburn, Alabama

Title: Myocardial Collagen Matrix Regulation During Ventricular Remodeling: The Role of the Cardiac Mast Cell
Host: Dr. Michael R. Zile
Sponsor: MCBP Program
Sep. 28, 2000 Neil Osheroff, Ph.D.
Professor , Department of Biochemistry
Vanderbilt University School of Medicine
Nashville, Tennessee

Title: The DNA Cleavage Reaction of Topoisomerase II, Dr. Jekyll or Mr. Hyde?
Host: Dr. Dan Fernandes
Sponsor: MCBP Program
Oct. 5, 2000 Jacqueline F McGinty, Ph.D.
Professor of Physiology and Neuroscience
Medical University of South Carolina
Charleston, South Carolina

Title: Brain Mechanisms Underlying Drug Abuse
 
Oct. 12, 2000 Denise Montell, Ph.D.
Associate Professor
Department of Biological Chemistry
Johns Hopkins School of Medicine
Baltimore, Maryland

Title: Changes in Gene Expression, Cell Adhesion and Actin Organization in the Developmental Control of Cell Migration
Host: Dr. Tien Hsu
Sponsor: MCBP Program
Oct. 19, 2000 Rudolph Juliano, Ph.D.
Professor and Chair
Department of Pharmacology
University of North Carolina
Chapel Hill, North Carolina

Title: Integrins and Signal Transduction
Host: Dr. Donald Menick
Sponsor: MCBP Program
Oct. 26, 2000 Donald R. Menick, Ph.D.
Associate Professor of Medicine, and Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Regulation of Gene Expression in Cardiac Hypertrophy and Failure
 
Nov. 2, 2000 Lynn M. Matrisian, Ph.D.
Professor and Chair
Department of Cancer Biology
Vanderbilt University
Nashville, Tennessee

Title: Matrix Metalloproteinases in Normal and Neoplastic Processes
Host: Dr. Frank Spinale
Sponsor: MCBP Program
Nov. 9, 2000 Sergey Krupenko, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, South Carolina

Title: Structure/Function Studies of a Major Folate Enzyme
 
Nov. 16, 2000 Peter Nelson, Ph.D.
Assistant Member
Division of Human Biology
Department of Molecular Biotechnology
Fred Hitchinson Cancer Research Center
University of Washington
Seattle, Washington

Title: Genome and Proteome Approaches for Charachterizing the Prostate Androgen-Response Program
Host: Dr. Dennis Watson
Sponsor: MCBP Program
Nov. 30, 2000 Charles N. Serhan, Ph.D.
Director, Center for Experimental Therapeutics and Reperfusion Injury
Professor of Anaesthesia (Biochemistry and Molecular Pharmacology)
Brigham and Women's Hospital/Harvard Medical School
Boston, Massachusetts

Title: Novel Arrays of Lipid Signals in Anti-inflammation
Host: Dr. Yusuf A. Hannun
Sponsor: MCBP Program
Dec. 7, 2000 Walter J. Koch, Ph.D.
Associate Professor
Department of Surgery and Pharmacology
Duke University Medical Center
Durham, North Carolina

Title: G Protein-coupled Receptor Kinases in the Cardiovascular System: Lessons Learned from Transgenic Mice

Host: Ashley Smithwick
Sponsor:
MCBP Program


Monday Noon Seminar Series Calendar
502 - Basic Science Building

FAll 2006-Spring 2007
FALL 2006
SPRING 2007

Sept. 4
(Labor Day)

No seminar

Jan 15
(MLK Day)

No seminar

Sept. 11

 

January 22

Loretta Hoover

Maria Vizcaino

Sept. 18

Jennifer Konopa-Mulligan

Jan 29

Colleen Bryan

Jennifer Yordy Meagan Mollenhauer

Sept 25

No Seminar

Feb 5

Liz Grant Burton

Jocelyn Flanary

Oct. 2

Julie Woolworth

Feb 12

Christina Grek

Shawn Polson
Oct. 9

Rany Abdallah

Feb 19 Tom Mullen
Arindam Saha Rebecca Johnston
Oct. 16 Wes Jackson
Feb 26 Chris Gault
Angela Ghatneka Jessica Shockey
Oct. 23 Michael O'Quinn
March 5 Hazitha Samuel
Erin Morris Stephanie Brunelle
Oct. 30
(SRD week)
Elaine Wirrig
Kelli Margot
March 12 Spring Break
No Seminar
Nov 6 Adrian Grimes
March 19 Tara Burns
Phil Moshchella Tod Leighfield
Nov 13 Emily Monroe
March 26

Brian Snarr

Kristie Lidie Youssef Zaidan
Nov 20 Jonathan Butler
April 2 Millie Embree
Blake Ellis Chris Potter
Nov 27 Matt Mains
April 9 Bobbie Lyon
Jason Guichard John Svenson
Dec 4

Ben Neely

April 16 Khaled Moussawi
Nathan Pruett Anand Shunmugavel
Dec 11 For emergency seminar only April 23 Matt Rhett
Arun Palanisamy
    April 30 For emergency seminar only

Autumn 2004
Spring 2005

Aug 30

No seminar
Sign-up only

Jan 10

Peko Tsuji
Tracey Schock

       

Sep 6

LABOR DAY

Jan 17 (MLK)

We will use this day only
if we are running out of slots

 

 

Sept 13

 

Jan 24

Chris Johnson
Megan Kibbey

 

 

Sept 20

Millie Embree

Feb 7

Peter Wieckowski
Ramandeep Rattan

 

 

Sept 27

 

Feb 14

Laura Spruill
Lena Heung

 

 

Oct 4

MUSC- Townhall meeting
In BSB 100

Feb 21

Frank Bartel
Christy Kappler

 

 

Oct 11

 

Mar 7

Gregor Krings
Shantae Jenkins

 

 

Oct 18

 

Mar 14

SPRING
BREAK

 

 

Oct 25

Jessica Petersen
Tarek Taha

Mar 21

David Arrington
Erin Egan

 

 

Nov 1

Jessica Shockey
Leslie Wooten

Mar 28

Anne Deschamps
Kevin Orwig

 

 

Nov 8
(Mon after SRD)

Jason Guichard
Adrian Grimes

April 4

Shawn Polson
Kristie Lidie

 

 

Nov 15
(thnxgiv wk)

Mara Lennard
Matt Jenny

April 11

Sara Polson
John Svensen

 

 

Nov 22

Amanda Galloway
Juan C. Varela

April 18

Jonathan Mitchell
Richard Peterson (?)

 

 

Nov 29

Michelle Hsia
Joy Van Nostrand

April 25

Javier Robalino
Arun Palanisamy

 

 

Dec 6

           

Eric Sribnick
Ratna Prasad

 

 

Spring 2002

January

14

Mark Pilgrim

 

21

Jeff Jones

 

28

Melissa Fraser

February

4

Ron Feldman

 

11

Benjamin Pettus

 

18

Michelle Crosby

 

25

Kevin Becker

March

4

Laura Columbo

 

11

Spring Break

 

18

Paula Acierno

 

25

Vijay Rao

April

1

David McLean

 

8

Nicole Redmond

 

15

Christopher Willey

 

22

Josh Hubbard

 

29

 

Fall 2001

August

27

Eric Grund
Yair Adereth
Amanda LaRue

September

10

Stephen Gee
Matthew Jenny
Andrew Whitlock

 

17

Christiana Kappler
Ravinder Pannu
Jeannette Weiner

 

24

Xingjun Wu
Mark Slomiany
Megan Kibbey

October

1

Robert Bowers
Michael Janech

 

8

Kerin McCormack
Beth Neilsen

 

15

Alan Frey (Kroc Lecture; hosted by Steve Tomlinson)

 

22

Sean Norman
Ashley Smithwick

 

29

Robert Smith
Brian Giles

November

5

Christopher Crosby
 

 

12

Jeannie Chapman

 

19

Frank Bartel

 

26

Elizabeth Chesterman

December

3

Kevin Orwig

 

 


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