Mentor: Dr. Greg Warr
Education:B.S. 1997, Escuela Superior Politecnica , M.S. 2000 Univ of Maryland, PhD 2006 MUSC
Year Graduated:
2006
Postdoctoral: Associate
Investigator, Escuela Superior Politecnica del Litoral, Guayaquil,
Ecuador
jrobalin@espol.edu.ec
robalino.javier@gmail.com
My research is focused on how invertebrates (especially marine invertebrates) defend themselves against viral pathogens. Such antiviral mechanisms are of great significance for both human and environmental health because 1) invertebrates (e.g. insects) are vectors of viral diseases affecting humans, 2) viruses are the most abundant class of microorganisms in the marine environment, and 3) many marine invertebrates are hosts to pathogenic viruses. We are using marine shrimp and some of its viruses as a model system to understand two key aspects of the antiviral response: first, what kind of molecular signatures are recognized by the invertebrate immune system as signals of viral infection, and second which host genes are regulated during infection by a viral pathogen, and during activation of the subsequent immune response.
PUBLICATIONS:
Induction of Antiviral
Immunity by Double-Stranded RNA in a Marine Invertebrate Javier
Robalino, Craig L. Browdy, Sarah Prior, Adrienne Metz, Pamela Parnell,
Paul Gross, and Gregory Warr,Journal of Virology, Oct. 2004, p. 10442-10448
Induction of General Antiviral Immunity by Double Stranded RNA in a
Marine
Invertebrate.,Javier Robalino, Craig L. Browdy , Sarah Prior , Adrienne Metz
,Pamela Parnell, Paul Gross ,, Gregory Warr ,*In press. J. Virol.Presentations
PRESENTATIONS
INSIGHTS INTO THE IMMUNE TRANSCRIPTOME OF THE SHRIMP Litopenaeus
vannamei: TISSUE-SPECIFIC SIGNATURES OF GENE EXPRESSION AND CHANGES IN
RESPONSE TO A LETHAL VIRAL INFECTION, Javier Robalino, Jonas Almeida,
David J. McKillen, Joan Colglazier, Harold F. Trent III, Ann Cheng,
Megan E. T. Peck, Robert W. Chapman, Paul S. Gross, Craig L. Browdy, and
Gregory W. Warr, MBES Student Research Open House 2006
ANTIVIRAL IMMUNITY INDUCED BY DOUBLE
STRANDED RNA IN A MARINE SHRIMP.,Javier Robalino, Thomas Bartlett,
Robert Chapman, Craig Browdy, Paul Gross and Gregory Warr, 2005 MBES
Student Research Open House
Antiviral immunity in a marine invertebrate,
Javier Robalino, Joan Colglazier, Sarah Prior, Pamela Parnell, David
McKillen, Ann Chen, Jonas Almeida, Robert Chapman, Paul Gross,
Craig Browdy and Gregory Warr, .2005 MUSC Student Research Day
Antiviral immunity in a marine invertebrate,
Javier Robalino, Sarah Prior, Adrienne Metz, Joan Colglazier, Robert
Chapman, Paul Gross, Craig Browdy, Greg Warr,2004 MUSC Student Research Day
AWARDS: El Circulo of Charleston Student
Award
MEETINGS
Functional Genomics and antiviral immunity in the marine shrimp,World Aquaculture Society Meeting, Honolulu, HI, March 1-5, 200
SACNAS (Society for the Advancement of Chicanos and Native Americans in
Science)
2004 Reverse Genetic Approaches in Shrimp: Unexpected Implications for
the Immune System,
Plant and Animal Genome Conference, San Diego, CA, January 15-20, 2005