Professor
Cell and Molecular Pharmacology
MUSC, Charleston. SC
Ph.D., Purdue University
scheykl@musc.edu
Proteomics of marine organisms. My marine biomedicine research interests are in the area of in shrimp and oysters. Protein analysis using state-of-the-art mass spectrometric techniques is used to identify protein modifications and changes in protein expression. This information will be used to understand underlying responses viral infection and stress in shrimp and to identify antimicrobial peptides in oysters.
Publications:
Walgren JLE, Vincent TS, Schey KL, Buse
MG: High glucose/insulin promote O-GlcNAc modification of proteins
including a-tubulin, Amer. J. Physiol. Endocrinol. Metab., 2003,
284:E424-434.
Hamilton MH, Cook LA, McRackan TR, Schey KL, Hildebrandt JD: Gamma-2
Subunit of G Protein Heterotrimer is an N-end Rule Ubiquitylation
Substrate, Proc. Natl. Acad. Sci., 2003, 100:5081-5084.
Nishida M, Schey KL, Takagahara S, Kontani K, Katada T, Urano Y, Nagano
T, Nagao T, and Kurose H: Activation Mechanism of Gi and Go by Reactive
Oxygen Species, J. Biol. Chem., 2002, 277:9036-9042.