Daniel W. Bearden, Ph.D. Research Chemist, National Ocean Service Ph.D., Rice University dan.bearden@noaa.gov
Research: Environmental contaminant analysis and environmental toxicology.  Our laboratory conducts research into new analytical chemistry methods for the detection and quantification of environmental compounds of interest. In addition, we conduct research in nuclear magnetic resonance (NMR) structure elucidation of natural products and biomolecular compounds (i.e., proteins). •    Nuclear magnetic resonance spectroscopy •    NMR-based marine metabonomics •    Environmental structural biology and natural products
Publications: J. E. Oatis, Jr., P. Brunsfeld, J. W. Rushing, P. D. Moeller, D. W. Bearden, T. N. Gallien, and G. Cooper, IV: Simplified Isolation and Purification of Cyclopamine from Veratrum californicum, (2008) accepted for publication in Chemistry Central Journal. N. Morrison, D. Bearden, J. G. Bundy, T. Collette, F. Currie, M. P. Davey, N. S. Haigh, D. Hancock, O. A. H. Jones, S. Rochfort, S. A. Sansone, D. Stys, Q. Teng, D. Field, M. R. Viant: Standard Reporting Requirements for Biological Samples in Metabolomics Experiments: Environmental Context, Metabolomics 3: 203-210 (2007). W.L. Balthis, J.L. Hyland, D.W. Bearden: Ecosystem Responses to Extreme Natural Events: Impacts of Three Sequential Hurricanes in Fall 1999 on Sediment Quality and Condition of Benthic Fauna in the Neuse River Estuary, North Carolina. Environmental Monitoring and Assessment 119(1-3): 367-389 (2006). M. H. Fulton, P. Key, E. Wirth, A. Leight, J. Daugomah, D. Bearden, S. Sivertsen, G. Scott: An Evaluation of Contaminated Estuarine Sites Using Sediment Quality Guidelines and Ecological Assessment Methodologies, Ecotoxicology 15(7): 573-581 (2006). J. Hyland, C. Cooksey, W. L. Balthis, M. Fulton, D. Bearden, G. McFall, M. Kendall: The soft-bottom macrobenthos of Gray’s Reef National Marine Sanctuary (GRNMS) and nearby shelf waters off the coast of Georgia, USA, Journal of Experimental Marine Biology and Ecology, 330: 307-326 (2006). R. F. Van Dolah, G. H. M. Riekerk, M. V. Levisen, G. I. Scott, M. H. Fulton, D. Bearden, S. Sivertsen, K. Chung, D. M. Sanger: An Evaluation of Polycyclic Aromatic Hydrocarbon (PAH) Runoff From Highways Into Estuarine Wetlands of South Carolina, Archives of Environmental Contamination and Toxicology, 49: 362-370 (2005). M. H. Fulton, G. I. Scott, M. E. DeLorenzo, P. B. Key, D. W. Bearden, E. D. Strozier, C. J. Madden: Surface Water Pesticide Movement from the Dade County Agricultural Area to the Everglades and Florida Bay via the C-111 Canal, Bulletin of Environmental Contaminant Toxicology 73: 527–534 (2004) E. F. Wirth, P.L Pennington, J. C Lawton, M. E. DeLorenzo, D. Bearden, B. Shaddrix, S. Sivertsen, M. H. Fulton: The Effects of the Contemporary-Use Insecticide (Fipronil) in an Estuarine Mesocosm, Environmental Pollution, 131: 365-371 (2004). L. L. Remsing, J. Garcia-Bernardo, A. Gonzalez, E. Kunzel, U. Rix, A. F. Bran, D. W. Bearden, C. Mendez, J. A. Salas, and J. Rohr: Ketopremithramycins and Ketomithramycins, Four New Aureolic Acid-Type Compounds Obtained upon Inactivation of Two Genes Involved in the Biosynthesis of the Deoxysugar Moieties of the Antitumor Drug Mithramycin by Streptomyces Argillaceus, Reveal Novel Insights into Post-PKS Tailoring Steps of the Mithramycin Biosynthetic Pathway, Journal of the American Chemical Society, 124: 1606-1614 (2002). C. Mendez, E. Kunzel, F. Lipata, F. Lombo, W. Cotham, M. Walla, D. W. Bearden, A. F. Brana, J. A. Salas, J. Rohr; Oviedomycin, an unusual angucyclinone encoded by genes of the oleandomycin-producer Streptomyces antibioticus Journal of Natural Products. 65(5):779-82 (2002).

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