Objective of grant: The aim of this program is to train a new generation of biostatisticians to assume key roles in the "omics" era of biomedical research. The program stresses the integration of biostatistical theory and methods, including nonlinear systems analysis and mathematical modeling, with tools from bioinformatics to address quantitative frontiers in modern multi-disciplinary biological research. The program incorporates entry level, broad-based didactic and laboratory training in the biomedical sciences and an established biostatistics program. Students work jointly with biostatistics and biomedical sciences faculty on the frontier of "omics" research.

Objective of grant: The overarching goal of this program is to promote biostatistics proficiency and expertise in neuroscience research. The ultimate goal is to develop PhD biostatisticians who will pursue research on statistical issues arising in neuroscience and who will form strong collaborative relationships with researchers in neuroscience.

Objective of grant: The goals of this program are to promote the participation of underrepresented groups in the biomedical sciences and prepare them for successful careers as research scientists.

Objective of grant: The main goal of this program is to address the national need for doctoral-trained scientists in biology and information sciences and provide quality teaching experiences for the graduate fellows with adequate instruction, supervision and instruction.

Objective of grant: The essential objectives of this program are to address the national need for doctoral-trained scientists in anatomy and equip graduate students with skills to teach anatomy by providing instruction in effective teaching, supervision and evaluation.

Objective of grant: The major goal of this grant is to develop a partnership between MUSC and the Charleston County School District to engage K-12 classrooms in inquiry teaching, learning and create a culture of cooperation between the scientific community and the classroom. Graduate student fellows bring their discoveries and excitement for investigation into classrooms while teachers acquire the tools to effectively transfer the excitement of discovery from the laboratory bench to the classroom.

Objective of grant: This program is designed to increase the number of well-trained clinical researchers who will assume leadership roles in the design, conduct and oversight of future clinical investigations. Eligible participants are predoctoral medical students, dental students, nursing students, students from the College of Health Professionals and students from the College of Graduate Studies. They will learn the principles and practice of clinical investigation and the application of cutting edge technology to clinical research.

Objective of grant: The goal of this program is to train physician-scientists to become leaders in academic medicine by providing in-depth training in how to synthesize the knowledge of basic science gained through research with clinical observation and experience gained during professional training. The ultimate goal is to produce trained professionals who chose a life-long career in biomedical research leading to the translation of fundamental discoveries into improved health care delivery.

Objective of grant: The major objective of this program is to train new scientists to address mechanisms of environmental stress signaling and cellular consequences and to translate their findings into the development of interventions or novel therapeutics that prevent or diminish cell injury, death, and carcinogenesis and/or promote repair and regeneration.

Objective of grant: The goals of this training program are to produce well-rounded individuals 1) who are knowledgeable about the basic science and clinical aspects of substance abuse; 2) who are familiar with treatment strategies, and 3) who are trained to appreciate and conduct independent research in the area of substance use, abuse and dependence.

Objective of grant: The overall goal of this program is to produce scientists knowledgeable in the field of substance abuse to conduct independent substance abuse research. A multidisciplinary mentor-apprenticeship model is used and training is complemented by seminars on substance abuse, the neurosciences, grant writing, statistics, ethics, and exposure to treatment strategies.

Objective of grant: Training in Bioinformatics is focused on theory identification and algorithm development for tool makers. The program reflects the biomedical research emphasis associated with a Medical University. The resulting multidisciplinary emphasis together with the integration with clinical outcomes establishes the stage for cutting edge computational biology research. Moreover, the proximity to the federal research facilities of NOAA and the Hollings Marine Laboratory promotes the integration in a wider biological framework. In particular, the training program reflects close interaction with the bioinformatics core and mathematical modeling projects of the NHLBI Proteomics Center as well as the hosting of the computational component of the Marine Genomics Initiative.

Objective of grant: Our objective is the training of promising new predoctorial and postdoctorial fellows with cutting edge experimental strategies, technologies and research experience necessary for understanding the molecular basis of cardiovascular disease and in the development of novel therapeutics targeting this devastating disease. The program focus is in three broad research areas: (1) mechanisms of cardiac failure, (2) signal transduction in hypertension, vascular disease and diabetes, and (3) developmental biology of the cardiovascular system. Our faculty is highly interactive in both predoctoral and postdoctoral training, and our postdoctoral students benefit in many ways from an organized graduate program in cardiovascular biology.

Objective of grant: The majors aims of this program are to 1) provide superior training in basic cardiovascular science research for clinically trained and Ph.D. postdoctoral investigators, 2) develop a clinical research training pathway for M.D./D.O. investigators and a translational research pathway for Ph.D. postdoctoral investigators, both of which are integrated with the Master of Science in Clinical Research program.

Objective of grant: The aim of this program is to produce academically oriented physicians and basic scientists with investigative expertise in diseases that affect the kidney. Training emphasizes the interplay between systemic diseases such as diabetes and hypertension, and local factors in the kidney, which may regulate the development of glomerular pathology.

Objective of grant: The program is designed to prepare physicians, post-doctoral nurses, and pharmacists for productive academic careers as educators and as investigators in Health Services Research.

Objective of grant: The emphasis of this program is on identifying and studying factors related to ethnic disparity in systemic lupus erythematosus and scleroderma in African Americans. Efforts focus on defining societal, environmental and genetic factors that impact morbidity and mortality in African Americans with rheumatic diseases.

Objective of grant: This is an NIH K12 career development award for postdoctoral scholars interested in a significant mentored teaching opportunity to complement their research training program. The MUSC and Claflin University cooperative blends the complementary strengths of both institutions, with the overall goal of facilitating the academic career development of MUSC postdoctoral scholars while simultaneously enriching the science and math curricula at Claflin. Individuals will receive a well-rounded experience in pedagogy at a primarily undergraduate institution from syllabus preparation, lecturing, and examination activities to holding office hours and participating in faculty meetings. Research activities, however, remain the main focus for the scholar, comprising 75% effort. The underlying hypothesis for this program is that the organizational, communication, and managerial skills learned in teaching translate into a more effective researcher.

Objective of grant: This interdisciplinary research training program in cancer therapeutics is designed to train promising young scientists with backgrounds in the biomedical sciences, with special emphasis on the management of cancer and the experimental strategies, approaches and technologies necessary to develop novel therapeutics targeting specific cancers.