Alexander Awgulewitsch, Ph.D. Associate Professor Rheumatology/Immunology Transgenic mouse models for skin cancer and the role of Hox genes in skin development & cancer Craig Beeson, Ph.D. Associate Professor Department of Pharmaceutical Sciences Development of topoisomerase I inhibitors Narayan R. Bhat, Ph.D. Professor Department of Neurology Growth factor signaling and gliomagenesis Robert J. Boackle, Ph.D. Professor of Immunology Professor and Director of Oral Biology, Department of Stomatology Mucosal immunity, inflammation, mucosal defense against HIV, complement chemistry, cancer immunotherapy Maria G. Buse, M.D. Professor, Division of Endocrinology Cell regulation and hormones in relation to cancer David J. Cole, M.D. Professor Department of Surgery Mechanisms of T-cell recognition of tumor antigens to translate into ongoing clinical cancer vaccine/gene therapy trials Christopher J. Drake, Ph.D. Professor Department of Cell Biology & Anatomy The control and regulation of neovascular processes (angiogenesis & vasculogenesis) in tumor growthand metastasis Weiman Fan, M.D., M.P.H. Professor Department of Pathology and Laboratory Medicine Molecular Oncology, experimental therapeutics, and tumor growth regulation Sebastiano Gattoni-Celli, M.D. Professor Radiation Oncology Immunotherapy of cancer Yusuf A. Hannun, M.D. Ralph F. Hirschmann Professor and Chairman Biochemistry and Molecular Biology Tumor promotion/apoptosis, cancer therapeutics Stanley R. Hoffman, Ph.D. Professor Rheumatology/Immunology Function of specific ECM proteins and MMP's in metastasis & tumaor angiogenesis Tien Hsu, Ph.D. Associate Professor Hollings Cancer Center Drosophila model systems for studying cancer-related gene functions Karl J. Karnaky, Ph.D. Associate Professor Cell Biology & Anatomy Role of membrane transporters, MRP1 and MRP2, in regulating exposure of human breast epithelial cells to xenobiotic and endogenous molecules Michael Kern, Ph.D. Associate Professor Cell Biology & Anatomy Target genes of homeobox transcription factors in cancer: microarrays and beyond. Steven W. Kubalak, Ph.D. Associate Professor Cell Biology & Anatomy Transforming growth factor-beta regulation of apoptosis Dhandapani Kuppuswamy, Ph.D. Associate Professor Department of Medicine, Division of Cardiology Use terminally differentiated cardiac cells to identify factors that could negatively influence cancer cell growth Runzhao Li, M.D., M.Sc. Assistant Professor Department of Medicine Center for Molecular & Structural Biology Modulation of Ets transcription factors in tumor angiogenesis and apoptosis protein-protein interaction and the signals in transcriptional control of Ets target genes. Gene therapy, application of tumor suppressor genes and oncogenes for developing new anti-neoplastic targets. Lucille London, B.S., Ph.D. Associate Professor Microbiology and Immunology Induction of diffuse alveolar damage: ARDS Ioanna Maroulakou, Ph.D. Assistant Professor of Medicine Laboratory of Cancer Genomics JoEllyn M. McMillan Assistant Professor Marine Biomedicine Mechanisms of hepatocarcinogenesis

Michael Mitas, M.D. Assistant Professor Department of Surgery Breast cancr diagnostics and detection of associated genes Robin C. Muise-Helmericks, Ph.D. Assistant Professor Cell Biology and Anatomy Hollings Cancer Institute Role of the Ets family of transcription factors in angiogenesis and lymphoid development Dr. James S. Norris, Ph.D. Professor and Chairman Microbiology & Immunology Apoptosis & apoptosis signaling, bystander effect, ceramide, combined chemotherapy-gene therapy, and apoptosis inducing gene FasL, TRAIL, & BAX Lina M. Obeid, M.D. Professor Role of sphingolipids in tumor angiogenesis Makio Ogawa, M.D., Ph.D. Professor Department of Medicine Division of Experimental Hematology Differentiation and proliferation of hemopoietic stem cells Besim Ogretmen, Ph.D. Assistant Professor Department of Biochemistry Regulation of telomerase and roles of sphingolipids in cancer chemotherapy Swapan K. Ray, Ph.D. Assistant Professor Department of Neurology Involvement of calpain, a Ca2+-dependent cysteine protease, in the molecular mechanisms of cell death in disorders and diseases of the central nervous system Steven A. Rosenzweig, Ph.D. Professor Cell and Molecular Pharmacology Tumorigenesis, angiogenesis, hypoxia-inducible factor, IGF-binding proteins, receptor tyrosine kinases, and protein:protein interactions Clifford W. Schweinfest, Ph.D. Professor Department of Experimental Oncology The role of the growth suppressor gene, DRA, in colorectal neoplasia and the role of mismatch repair genes in prostate cancer Eleanor K. Spicer, Ph.D. Associate Professor Biochemistry and Molecular Biology Post-transcriptional regulation of human bcl-2 expression Demetri D. Spyropoulos, Ph.D. Assistant Professor Department of Medicine Lymphoid, breast, bladder, prostate, & colon cancer Stephen Tomlinson, Ph.D. Associate Professor Microbiology & Immunology Role of complement & complement inhibitors in tumorigenesis and immune response to cancer Bryan Toole, Ph.D. Professor MCBP Hyaluronan and emmprin in cell survival signaling pathways, multidrug resistance, epithelial-mesenchymal transition, angiogenesis and invasiveness in cancer Maria Trojanowska, Ph.D. Professor Rheumatology/Immunology The role of stromal cells in tumor growth and progression Irene Y. Wang, Ph.D. Associate Professor Biochemistry and Molecular Biology Construction and expression of mouse-human chimeric antibodies toward human colon and lung cancers Thomas Walle, Ph.D. Professor Professor of Cell and Molecular Pharmacology Carcinogenesis: prevention and toxicology Dennis K. Watson, Ph.D. Professor Laboratory of Cancer Genomics Pathology & Laboratory Medicine Mechanisms of cancer initiation, progression, and metastasis M. Rita I. Young, Ph.D. Professor of Medicine Department of Hematology Oncology Cancer motility, Angiogenesis, Imunotherapy

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