The MUSC BSL has been a pioneer in trying to understand
what VNS is doing in the brain. Here are important manuscripts in these
new areas.
Bohning DE, Lomarev MP, Denslow S, Nahas Z, Shastri A, George MS. Feasibility of vagus nerve stimulation-synchronized blood oxygenation level-dependent functional MRI. Invest Radiol. Aug 2001;36(8):470-479.
Lomarev M, Denslow S, Nahas Z, Chae JH, George MS, Bohning DE. Vagus nerve stimulation (VNS) synchronized BOLD fMRI suggests that VNS in depressed adults has frequency/dose dependent effects. J Psychiatr Res. Jul-Aug 2002;36(4):219-227.
Mu Q, Bohning DE, Nahas Z, Walker J, Anderson B, Johnson KA, Denslow S, Lomarev M, Moghadam P, Chae JH, George MS. Acute vagus nerve stimulation using different pulse widths produces varying brain effects. Biol Psychiatry. Apr 15 2004;55(8):816-825.
Conway CR, Sheline YI, Chibnall JT, George MS, Fletcher JW, Mintun MA. Cerebral blood flow changes during vagus nerve stimulation for depression. Psychiatry Research. Mar 31 2006;146(2):179-184.
Borckardt JJ, Kozel FA, Anderson B, Walker A, George MS. Vagus nerve stimulation affects pain perception in depressed adults. Pain Res Manag. Spring 2005;10(1):9-14.
Borckardt JJ, Anderson B, Kozel
FA, Nahas Z, Smith AR, Thomas KJ, Kose S, George MS. Acute and
Long-term VNS Effects on Pain Perception in a Case of
Treatment-Resistant Depression. Neurocase. 2006;12(4):216-220.