Publications
Swan, M.K., Hansen, T., Schönheit, P. & Davies, C. (2004) The structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from P. aerophilum: a subtle difference between distantly related enzymes. Biochemistry, 43: 14088-14095.     
  :1GZD, 1GZV
 
Solomons, J.T.G., Zimmerly, E.M., Burns, S., Krishnamurthy, N., Swan, M.K., Krings, S., Muirhead, H., Chirgwin, J. & Davies, C. (2004) The crystal structure of mouse phosphoglucose isomerase at 1.6 Å resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening. J. Mol. Biol., 342: 847-860.
 
Swan,M.K., Hansen, T., Schönheit, P. & Davies, C. (2004) A novel phosphoglucose isomerase/phosphomannose isomerase from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16Å resolution. J. Biol. Chem. 279: 39838-39845.
 
Swan, M.K., Hansen, T., Schönheit, P. & Davies, C. (2004) Crystallisation and preliminary x-ray diffraction analysis of phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum. Acta Cryst., D60: 1481-1483.
 
Chumanevich, A.A., Krupenko, S.A. & Davies, C. (2004) The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain. J. Biol. Chem., 279: 14355-14364.
 
Stefanova, M.E., Tomberg, J., Davies, C., Nicholas, R.A. & Gutheil, W.G. (2004) Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4. Eur. J. Biochem., 271: 23-32.
 
Nicholas, R.A., Krings, S., Tomberg, J., Nicola, G. & Davies, C. (2003) Crystal structure of wild-type penicillin-binding protein 5 from E. coli:  Implications for deacylation of the acyl-enzyme complex. J. Biol. Chem. 278: 52826-52833.
 
Swan, M.K., Solomons, J.T.G., Beesen CC., Hansen, T., Schönheit, P. & Davies, C. (2003) Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus. J. Biol. Chem., 278: 47261-47268.
 
Swan, M.K., Hansen, T., Schönheit, P. & Davies, C. (2003) Crystallization and preliminary x-ray diffraction analysis of phosphoglucose isomerase from Pyrococcus furiosus. Prot. Pept. Letts., 10: 517-520.
 
Davies, C., Muirhead, H. & Chirgwin, J. (2003) The structure of human phosphoglucose isomerase complexed with a transition-state analogue. Acta Cryst., D59: 1111-1113.
 
Davies, C. & Muirhead, H. (2003) The crystal structure of native phosphoglucose isomerase from rabbit:  conformational changes associated with catalytic function. Acta Cryst., D59: 453-465.
 
Davies, C. & Muirhead, H. (2002) The crystal structure of pig phosphoglucose isomerase from pig muscle and its complex with 5-phosphoarabinonate. Prot. Struc. Fun. Gen., 50: 577-579.
 
Chumanevich, A.C., Davies, C. & Krupenko, S.A. (2002) Crystallization and preliminary X-ray diffraction analysis of recombinant hydrolase domain of 10-formyltetrahydrofolate dehydrogenase. Acta Cryst., D58: 1841-1842.
 
Stefanova, M.E., Davies, C., Nicholas, R.A. & Gutheil, W.G. (2002) pH, inhibitor and substrate specificity studies on Escherichia coli Penicillin-Binding Protein 5. Biochim Biophys. Acta 1597: 292-300.
 
Read, J., Pearce, J. Li, X., Muirhead, H., Chirgwin, J. & Davies, C. (2001). The crystal structure of human phosphoglucose isomerase at 1.6 Å resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia. J. Mol. Biol. 309, 447-464.
 
Davies, C., White, S.W., and Nicholas, R.A. (2001) Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3 Å resolution. J. Biol. Chem. 276, 616-623.