| Faculty Member |
Research
Interests |
A
|
|
| B |
|
|
Bastia, Deepak |
Analyses
of (1) the mechanisms of initiation of DNA replication
of prokaryotic plasmids and (2) the termination of DNA
replication of plasmid, bacterial and yeast
chromosomal, and human mitochondrial DNA
|
|
Bielawska, Alicja |
Role of
sphingolipids in signal transduction and cell
regulation with emphasis on cancer biology. Specific
interest is related to the regulatory function of
ceramide and sphingosine-1-phosphate.
Development of molecular and analytical tools to study
mechanism of biological action of sphingolipids in
relation to their physicochemical properties.
|
|
Bielawski, Jacek |
Sphingolipids in Signal Transduction
Cell Regulation in Cancer Biology
Development of new analytical protocols
|
|
Bullesbach, Erika |
Hormones
of Insulin-Like Structure:
Chemical Syntheses and Structure-Function Relations
|
|
C |
|
|
Chao, Julie |
Serine
Proteinase Structure-Function Relationship;
Purification, Molecular Cloning, Expression, and
Function of Proteinases and Proteinase Inhibitors;
Serpin Regulation of Gene Expression
|
|
Chao, Lee |
Nucleic
Acid Biochemistry;
Regulatory Mechanism in Gene Expression;
Gene Therapy in Cardiovascular Diseases
|
|
D |
|
|
Davies, Christopher |
Using
X-ray crystallography to determine the structures of
medically and biologically important macromolecules
|
|
Del Poeta,
Maurizio |
Role
and Regulation of inositol-phosphoryl-ceramide
synthase (Ipc1) in pathogenic fungi
Role and Regulation of enzymes involved in the
degradation of sphingolipids
|
|
Duggan,
Brendan M |
Biological function at the molecular level
biophysical techniques such as NMR, ITC and CD to characterize the three dimensional
structure and internal dynamics of biomolecules
|
|
F |
|
| Fernandes, Daniel |
Molecular
mechanisms of drug-induced gene amplification
Interactions of anticancer drugs with nuclear matrix
proteins, especially DNA topoisomerase II
|
|
G |
|
|
H |
|
| Hama, Hiroko |
Lipid regulation of cellular processes
Phosphatidylinositol 4-phosphate in protein secretion
Sphingolipid hydroxylation
Saccharomyces
cerevisiae
|
|
Hannun, Yusuf |
Role and
Regulation of Protein Kinase C Isoenzymes
Sphingomyelin Turnover and Cellular Regulation
The Sphingomyelin/Ceramide Cycle as a Novel Target for
Apoptosis and Inflammatory Disease Interventions
Ceramide Activated Protein Phosphatases
|
Hansen, Debra Tumbula
|
Structure and assembly of telomerase
RNA/protein complexes |
| Hansen, Jeffrey L. |
Study of RNA/protein complexes through
x-ray crystallography; Telomerase
|
Heise, Tilman |
|
| |
|
Hennig, Mirko |
Structural Studies of RNA-ligand complexes using NMR Spectroscopy
|
| |
|
Hsu, Yi-Te |
Molecular mechanisms of apoptosis
Bcl-2, Bcl-XL
|
I
|
|
J
|
|
|
K |
|
|
Krupenko, Natalia |
Folate and
Methyl Group Metabolism
Glycine N-Methyltransferase (GNMT)
|
|
Krupenko, Sergey |
Protein
Structure and Function
Enzyme Mechanisms and Regulation
Folate Metabolism and Carcinogenesis
|
|
L |
|
Lemasters, John J
|
Cellular and molecular mechanisms of apoptosis and necrosis;
organ preservation for transplantation surgery;
mitochondrial physiology and pathophysiology, including mitochondrial permeability transition, mitophagy and calcium homeostasis;
oxidative stress;
ischemia/reperfusion; confocal and multiphoton microscopy of living cells. |
|
M |
|
| |
|
|
Mohanty, Bidyut |
Genome integrity.
DNA replication arrest-dependent homologous recombination
|
|
O |
|
|
Ogretmen, Besim |
Roles of sphingolipid metabolism in cancer pathogenesis, chemotherapy-induced cell death, and drug resistance
|
|
P |
|
| |
|
Q
|
|
R
|
|
|
S |
|
|
Schwabe, Christian |
Protein
Chemistry;
Biochemical Evolution;
Chemical Endocrinology
|
| |
|
Sommer, Gunhild |
|
| |
|
|
|
|
|
Spicer, Eleanor |
Post Transcriptional Regulation of Bcl-2 Gene
Expression;
Regulation of human oncostatin M expression;
mRNA stability |
|
Stillway, Bill |
Medical
education;
Lipid metabolism
|
|
Szulc, Zdzislaw |
Chemical
etiology of sphingolipids structure and functions
|
T
|
|
U
|
|
V
|
|
|
W |
|
|
Warr, Gregory |
Molecular
Evolution,
Origins of Immune Recognition;
Immunoglobulin Gene Structure and Expression
|
X
|
|
Y
|
|
Z
|
|