Schedule

Objectives

Exams

Course Director: Dr. Lee Chao, Professor of Biochemistry

Credit: 3 Semester Hours

Time: 3 one-hour lectures per week

Schedule Summary

Textbook: Biochemistry, 5th edition, 2002 by Jeremy M. Berg, John L. Tymoczko, Lubert Stryer.

Faculty:

Dr. Lee Chao, 535-C BSB, Phone: 792-5786

Dr. Natalia Krupenko, 733D BSB, 792-0013

Dr. Besim Ogretmen, 512-A HCC, 856-5192

Dr. Mirko Hennig, 535-D BSB, Phone: 792-7336

Course Objectives:

This is a Basic Biochemistry course and its goal is to teach the students a basic understanding of biochemical processes. Areas which will be emphasized will be: 1. acid-base relationships; 2. amino acids, metabolism, structure and pH relationships; 3. proteins, biosynthesis, characteristics and structure-function relationships; 4. oxygen transport, hemoglobin and myoglobin, factors affecting oxygen transport; 5. enzymes, kinetics, activation and regulation of activity; 6. metabolism, glycolysis, citric acid cycle, oxidative phosphorylation, pentose phosphate pathway, regulation of glycogen metabolism, metabolism of amino acids, fatty acids, and nucleotides and the role of vitamins in metabolism; 7. molecular biology, nature of th genetic material, DNA biosynthesis (replication), RNA biosynthesis (transcription); 8. protein synthesis (translation) and degradation; 9. collagen, properties, biosynthesis and degradation by collagenases, 10. regulation of gene expression in procaryotes and eucaryotes; and 11. introduction to genetic engineering.

The students will obtain a level of competence which will enable them to understand the biochemical and dental literature, especially as related to Dental Medicine, and to master other basic science courses, such as Immunology, Microbiology, Pharmacology, Physiology and Pathology.

Exams:

1. All examinations will be given in Room 302 BSDB.

2. All review sessions will be conducted in Room 302 BSDB.

3. All corrections of grading errors must be taken care of within one week of grade posting.

4. The final grade will be based on the average of the three one-hour exams and the final exam. The final exam has two parts. Part I is the fourth hourly exam. Part II is the cumulative final exam.

Additional Examination Guidelines:

Attached is a copy of exam rules recommended by the Student Government Association. Where possible, we will adhere to these rules. You are expected to be on time for these exams and to hand them in by or before the end of the period. Please do not ask questions during exams unless you wish to ask about a possible error on an exam question. Exam grades will be posted as soon as possible after the exam.

Special Note: In the event of student illness on examination day, the course coordinator should be contacted on or before that day. Make-up exams will be given to those students who have a valid, written excuse from a physician. Students are responsible for arranging a make-up exam as soon as possible.

In an attempt to make grades meaningful and to prevent collaborative efforts on the examination, the following suggestions have been made and will be followed.

1. Do not overcrowd. When necessary, more than one room should be used.

2. Proctor examinations with sufficient people as to be effective.

3. Separate individuals by one role of seats.

4. Take swift, quiet, corrective steps in any violation or violation attempts.

5. Require that all books, pads, et cetera, be left either outside of the testing room or away from the testing group.

6. Take care not to divulge answers to test questions when answering questions concerning the examination.

The instructor will feel free to quiz or examine students in any format including pop quizzes, questions requiring written answers and homework assignments, in addition to regular examinations. Performance on pop quizzes and/or homework assignments will be considered in the assignment of students final grade.