Course Director: Daniel J. Fernandes, Ph.D., D.Sc., Professor of Biochemistry
Credit: 2 Semester Hours
Time: 2 one-hour lectures per week; Tuesday and Thursday, 2:00 p.m. - 3:00 p.m.
Place: 402 BSB
Primary Textbook: Harper'sIllustrated Biochemistry, by R.K. Murray et al., 26th edition, 2000 (ISBN# 0-07-121766-5)
Secondary Textbook: Marks Basic Medical Biochemistry, A Clinical Approach, 2nd edition, 2004 (ISBN# 0-7817-2145-8)
Faculty:
Dr. Daniel J. Fernandes, Room 220 HCC, 792-1449, fernand@musc.edu Dr. Eamon Duke, Room 535 BSB, 792-4321 Ms. Megan Kibbey, Room 318 BSB, 792-8283, kibbeymm@musc.edu
Course Objectives:
This is an advanced course in biochemistry that emphasizes the structure/function relationships of macromolecules which comprise tissues of the oral cavity. In addition the molecular basis of certain diseases of the oral cavity, such as diabetes oral cancer, will also be covered. Topics will include collagen, calcium and fluoride metabolism, wound healing, salivary proteins, immunoglobulins, inflammation and blood coagulation. Students will also receive the latest information regarding the genetic alterations that lead to oral cancer as well as applications of genetic technology and tissue engineering to the practice of modern dentistry..
Examinations:
The final grade will be based on the average of the three examinations. The final exam will also include some questions based on information given in sections one and two. All examinations will be closesd-book and will cover material in the lectures, handouts, and the primary textbook (Harper's Illustrated Biochemistry). Possession and/or distribution of the contents of examinations is a violation of the Honor Code.
